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http://dx.doi.org/10.1111/trf.18220 | DOI Listing |
Indian Pediatr
September 2025
Multidisciplinary Research Unit, RNT Medical College, Udaipur, Rajasthan, India.
Objective: To estimate the prevalence of various hemoglobinopathies among newborns, women in antenatal clinic and children presenting with signs and symptoms suggestive of sickle cell disease (SCD).
Methods: A hospital-based prospective study was conducted at a Centre of Excellence for SCD (COESCD). Dried blood spot (DBS) samples were collected for newborn screening using heel-prick and venous samples were used in the post-neonatal age group.
Front Pharmacol
August 2025
School of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Ethnopharmacological Relevance: Baicalin, an extract derived from the dried root of Scutellaria baicalensis Georgi (Huang Qin), has demonstrated neuroprotective properties. Nonetheless, the safety profile of baicalin has not yet been fully elucidated.
Aim Of The Study: The objective was to characterize the acute and subacute toxicity profiles of baicalin across various organ systems, thereby establishing safe therapeutic windows for its clinical application in the treatment of chronic neurodegenerative disorders.
Biotechnol Appl Biochem
September 2025
Department of Molecular Biology and Genetics, Faculty of Science, Atatürk University, Erzurum, Turkey.
This study involved the isolation of ten psychrophilic bacterial strains from cold water in Söğütlü village, Erzurum. Following isolation, the strains were characterized using molecular and conventional methods. On the basis of the results of Petri dish assays, Aeromonas salmonicida subsp.
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September 2025
Department of Chemistry, Faculty of Mathematics and Natural Sciences, University of Oslo, 0371, Oslo, Norway; Hybrid Technology Hub - Centre of Excellence, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0315, Oslo, Norway. Electronic address:
Dried blood spots (DBS) offer a practical and relatively non-invasive method for sample collection. Here, we evaluate the feasibility of applying H NMR spectroscopy to metabolomic analysis of DBS. Various solvent suppression techniques and extraction protocols were tested using aqueous and methanolic solvents.
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September 2025
IRCCS Istituto delle Scienze Neurologiche di Bologna, Full Member of the European Reference Network for Rare and Complex Epilepsies (EpiCARE), Bologna, Italy.