Dura Closure Tactics to Prevent CSF Leakage in Microvascular Decompression Surgery.

Life (Basel)

Department of Neurosurgery, Konkuk University Medical Center, Seoul 05030, Republic of Korea.

Published: April 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

(1) Background: Achieving a complete and secure dural closure to prevent cerebrospinal fluid (CSF) leakage is a critical concern in microvascular decompression (MVD). Proper dural closure minimizes complications, such as infections caused by CSF leakage. This study introduces a novel three-step dural suturing method, termed the "triple-layer closing technique". (2) Methods: From September 2020 to March 2023, a total of 475 patients underwent MVD surgery at our institution, all of whom received dural closure using the triple-layer closing technique. This technique incorporates three layers: Duragen (synthetic dura, Integra Lifesciences), TachoSil (collagen matrix, Nycomed), and polymethyl methacrylate (PMMC) bone cement. Postoperative complications, including CSF leakage and infections, were retrospectively analyzed. (3) Results: CSF leakage was observed in five patients (1.1%), all of whom presented with CSF rhinorrhea and radiological evidence of effusion within the mastoid air cells. These patients were successfully treated with lumbar drainage, and none required reoperation. No other postoperative infections or complications were reported. (4) Conclusions: The triple-layer closing technique, utilizing Duragen, TachoSil, and PMMC bone cement, is an effective and reliable method for dural closure. This technique significantly reduces the risk of CSF leakage and surgical site infections, enhancing postoperative outcomes in MVD procedures.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12028582PMC
http://dx.doi.org/10.3390/life15040574DOI Listing

Publication Analysis

Top Keywords

csf leakage
24
dural closure
16
microvascular decompression
8
triple-layer closing
8
closing technique
8
pmmc bone
8
bone cement
8
csf
7
leakage
6
dural
5

Similar Publications

Background: Meningitis following cerebrospinal fluid (CSF) leak is associated with substantial morbidity and mortality. Current strategies for prevention, therapeutic options, and surgical timing lack consensus due to insufficient risk stratification tools. This study aimed to identify meningitis risk determinants and develop a predictive model to facilitate early detection in CSF leak patients.

View Article and Find Full Text PDF

Objective: To summarize the outcomes of 1000 consecutive microsurgical resection of cerebellopontine angle tumors.

Study Design: Retrospective cohort study.

Setting: Single tertiary care institution.

View Article and Find Full Text PDF

Background: Intracranial hypotension (IH) is a secondary headache syndrome that can result from spontaneous or iatrogenic CSF leaks. Subdural hematomas (SDHs) are a particularly dangerous sequela of IH. Although epidural blood patch (EBP) is a recognized treatment for IH, its use in pediatric patients with SDH as a solitary intervention has not been reported.

View Article and Find Full Text PDF

Spontaneous intracranial hypotension (SIH) is caused by cerebrospinal fluid leak and has an incidence of approximately five per 100,000 person-years. SIH leads to a range of clinical symptoms, from debilitating postural headaches to subdural hematomas (SDHs). The pathophysiology of the disease is not fully understood, but has garnered interest in recent years.

View Article and Find Full Text PDF

Background: Arnold-Chiari Malformation Type I (ACM-I) is a congenital disorder that can lead to severe neurological symptoms. While decompression surgery is the standard treatment, postoperative complications such as cerebrospinal fluid (CSF) leakage and infections can result in critical outcomes. Here, we report a case of septic shock following decompression surgery in a patient with ACM-I, emphasizing the challenges in postoperative critical care management.

View Article and Find Full Text PDF