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http://dx.doi.org/10.1016/j.msard.2025.106396 | DOI Listing |
Black hairy tongue (BHT), or lingua villosa nigra, is a rare adverse effect of linezolid, an antibiotic frequently used in the treatment of multidrug-resistant tuberculosis (MDR-TB). We present a case of a 24-year-old female who developed BHT while receiving linezolid as part of a longer regimen for MDR-TB. The patient exhibited a typical BHT presentation, with painless brown-to-black discoloration on the posterior dorsal surface of her tongue, appearing 25 days after initiating linezolid therapy.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Pathology and Laboratory Diagnosis, College of Veterinary Medicine, Qassim University, Buraydah, Saudi Arabia.
Tuberculosis (TB) remains one of the leading causes of infectious disease mortality worldwide, increasingly complicated by the emergence of drug-resistant strains and limitations in existing diagnostic and therapeutic strategies. Despite decades of global efforts, the disease continues to impose a significant burden, particularly in low- and middle-income countries (LMICs) where health system weaknesses hinder progress. This comprehensive review explores recent advancements in TB diagnostics, antimicrobial resistance (AMR surveillance), treatment strategies, and vaccine development.
View Article and Find Full Text PDFCureus
August 2025
Internal Medicine, Good Shepherd Hospital, Vythiri, IND.
Hypereosinophilic syndrome (HES) is a rare disorder marked by sustained blood eosinophilia and associated tissue or organ damage in the absence of a secondary identifiable cause. Eosinophilic ascites and pleural effusion are extremely rare clinical presentations of idiopathic HES and often mimic malignancy, tuberculosis, or parasitic infections. We report a case of idiopathic HES in a 68-year-old male presenting with exudative eosinophilic ascites and pleural effusion.
View Article and Find Full Text PDFNed Tijdschr Tandheelkd
September 2025
the Department of Internal Medicine, University Medical Center Groningen (UMCG).
A 27-year-old man from Ethiopia had undergone an extraction of a molar in Libya ten months earlier, after which a submental swelling developed. For that reason, an oral and maxillofacial surgery department was consulted. Clinical examination showed a tender, firm-to-the-touch, non-mobile swelling with central ulceration.
View Article and Find Full Text PDFActa Ortop Mex
September 2025
Universidad de Manizales. Colombia.
Articular tuberculosis is a rare condition, with extrapulmonary presentations most commonly appearing in joints such as the hip or knee. It is usually associated with conditions like immunosuppression or a history of pulmonary tuberculosis. Diagnosis involves imaging or pathology, and treatment typically involves surgical intervention along with medication.
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