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An understanding of the spatiotemporal behaviour of Meteorological drought (MD) and Hydrological drought (HD) is crucial for analysing how drought propagation occurs. Here, drought events were treated as three-dimensional grid structures spanning space (latitude and longitude) and time. 31 years (1971-2001) of global MD and HD events were analysed for evidence of propagation, and the most severe 20 MD events explored in detail. From the Inter-Sectoral Impact Model Intercomparison Project (ISIMIP) data archive, precipitation data was used for identifying MD events and an ensemble of simulated runoff from several global hydrological models used for detecting HD events. A technique was developed based on overlapping of the spatial and temporal coverage of MD and HD events, to establish propagation, and to calculate several propagation features. In three dimensions, the transformation from MD to HD was characterised based on delayed instigation, elongated duration, and dampened intensity of the HD event. Additionally, pooling of MD events that resulted in one or multiple branched HD events were identified. Results indicate that minor MD events with short durations and small areas generally do not exhibit propagation. The frequency of HD events with drought duration of 6-12-months is higher than that of MD events with 6-12-month duration. Out of 1740 extreme MD events identified for the 31-year period, 272 events propagated and resulted in 395 extreme HD events. Propagation features for the 20 most severe MD events show substantial variation based on geographical location highlighting the influence of regional climatic and hydrological conditions. This study advances the understanding of global drought propagation mechanisms by addressing key methodological challenges and providing a structured framework for future large-scale drought assessments.
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http://dx.doi.org/10.1016/j.scitotenv.2025.179486 | DOI Listing |
Eur J Cardiothorac Surg
September 2025
Department of Cardiovascular Surgery, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka-shi, Saitama, 350-1298, Japan.
Objectives: Coronary artery bypass grafting (CABG) using bilateral internal thoracic artery (BITA) conduits can achieve good outcomes for multivessel lesions. This study evaluated early angiographic patency and outcomes following off-pump CABG (OPCAB) using only in situ BITA and right gastroepiploic artery (rGEA) grafts.
Methods: This retrospective analysis included patients undergoing OPCAB using only in situ skeletonized BITA and rGEA grafts (July 2007 to March 2019).
JMIR Res Protoc
September 2025
Center for Alcohol & Addiction Studies, School of Public Health, Brown University, Providence, RI, United States.
Background: Digital media frequently contains positive portrayals of alcohol content, which has been shown to be associated with alcohol-related cognitions and behaviors. Because youth are heavy media consumers and have access to unsupervised, repeat viewing of media content on their personal mobile devices, it is critical to understand the frequency of encountering alcohol content in adolescents' daily lives and how adolescents engage with the content.
Objective: This paper outlines the study protocol for examining adolescents' exposure to alcohol-related content in digital media within their natural environments.
JAMA Intern Med
September 2025
Bayer CC AG, Basel, Switzerland.
Importance: There is an unmet need for long-term, safe, effective, and hormone-free treatments for menopausal symptoms, including vasomotor symptoms (VMS) and sleep disturbances.
Objective: To evaluate the 52-week efficacy and safety of elinzanetant, a dual neurokinin-targeted therapy, for treating moderate to severe VMS associated with menopause.
Design, Setting, And Participants: OASIS-3 was a double-blind, placebo-controlled, randomized phase 3 clinical trial that was conducted at 83 sites in North America and Europe from August 27, 2021, to February 12, 2024, and included postmenopausal women aged 40 to 65 years who were seeking treatment for moderate to severe VMS (no requirement for a minimum number of VMS events per week).
JAMA
September 2025
Department of Obstetrics and Gynecology, Máxima Medical Center, Veldhoven, the Netherlands.
Importance: Pregnant individuals with polycystic ovary syndrome (PCOS) present with a higher risk of pregnancy complications, including gestational diabetes, preeclampsia, and preterm birth. Myo-inositol supplementation may reduce these risks.
Objective: To determine whether daily supplementation with myo-inositol during pregnancy among individuals with PCOS reduces the risk of a composite outcome of gestational diabetes, preeclampsia, and preterm birth.
JAMA Pediatr
September 2025
Department of Health Policy and Management, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Importance: For the first time in nearly 2 decades, the US infant mortality rate has increased, coinciding with a rise in overdose-related deaths as a leading cause of pregnancy-associated mortality in some states. Prematurity and low birth weight-often linked to opioid use in pregnancy-are major contributors.
Objective: To assess the health and economic impact of perinatal opioid use disorder (OUD) treatment on maternal and postpartum health, infant health in the first year of life, and infant long-term health.