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http://dx.doi.org/10.1016/j.jcin.2025.02.026 | DOI Listing |
Rev Cardiovasc Med
August 2025
Department of Cardiology, Harbin Medical University, 150000 Harbin, Heilongjiang, China.
Background: Differences between female and male patients may influence the outcomes of transcatheter aortic valve replacement (TAVR). However, knowledge regarding known sex differences in TAVR procedures among Chinese people remains limited. Therefore, this study aimed to investigate the impact of sex-related differences on reverse left ventricular (LV) remodeling following TAVR in the Chinese population.
View Article and Find Full Text PDFClin Res Cardiol
September 2025
AGEL Hospital Trinec-Podlesi, Konska 453, Trinec, 739 61, Czech Republic.
Background: Pulmonary hypertension (PH) often coexists in patients undergoing transcatheter edge-to-edge mitral valve repair procedure (M-TEER). Its pre-procedural severity is considered a negative prognostic marker. Whether the post-procedural PH resulting from M-TEER can also serve as a long-term prognostic marker is unknown.
View Article and Find Full Text PDFJTCVS Open
August 2025
The State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing, China.
Objectives: Left ventricular vortex dynamics play a crucial role in cardiac function but are significantly altered by mitral valve diseases or surgical interventions. Such hemodynamic changes may lead to maladaptive intracardiac vortices, potentially triggering pathways associated with progressive left ventricular remodeling and thrombosis. This study assessed left ventricular hemodynamics under both physiological and pathological conditions using a biohybrid in vitro platform, aiming to analyze the impact of these conditions on cardiac function.
View Article and Find Full Text PDFHeart
September 2025
Department of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Background: Coaptation gap (CG) is one of the challenging anatomies of mitral transcatheter edge-to-edge repair (TEER), but its impact on patient outcomes is unclear. This study aimed to evaluate the impact of CG on procedural and clinical outcomes in patients with functional mitral regurgitation (MR).
Methods: Data from 2140 patients undergoing TEER for functional MR were analysed, focusing on the presence of CG, which is a missing leaflet coaptation between the anterior and posterior leaflets during systole.
Struct Heart
September 2025
Heart and Vascular Institute, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
•Outcomes of surgical aortic valve replacement + coronary artery bypass grafting vs. transcatheter aortic valve replacement (TAVR) + percutaneous coronary intervention (PCI) in severe aortic stenosis and coronary artery disease patients.•TAVR + PCI had lower 30-day acute kidney injury and bleeding, similar 2-year mortality/stroke.
View Article and Find Full Text PDF