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Article Abstract
This study characterizes two species of the genus Hypericum to envisage their applicability as effective and versatile functional foods, dietary supplements, and food preservatives. A wide phenolic composition was found in both extracts, highlighting flanovoids for H. japonicum and xanthones for H. sampsonii. Moreover, anthocyanins were analyzed for the first time in the latter plant. Antioxidant capacity was highlighted by oxidative hemolysis inhibition assay (OxHLIA), where H. japonicum was more effective (lower EC) than antioxidant Trolox (16.3 < 21.8 μg/mL). H. sampsonii extract inhibited lipid peroxidation in the thiobarbituric acid reactive substances (TBARS) method (EC = 17.05 μg/mL) compared to Trolox (EC = 5.8 μg/mL). H. japonicum antibacterial activity showed a minimum inhibitory concentration (MIC) of 0.007 mg/mL, even lower than the control. These results indicate the bioactive potential of both extracts, as well as the importance of evaluating the food-related bioactive components of medicinal plants and the mechanisms involved in their bioactivities.
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