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The WHO 2021-2030 roadmap for neglected tropical diseases (NTDs) and the 2022 Kigali Declaration urge academic research institutions to unite in combating NTDs, including schistosomiasis, and emphasize the importance of strategic partnerships to free more than 1 billion people who require interventions against NTDs. We conducted stakeholder meetings to understand the landscape of schistosomiasis research training in Uganda and the existing collaborations with research institutions in sub-Saharan Africa, Europe, the United Kingdom, and the United States. In focus group discussions (involving 33 individuals from four institutions), key challenges were summarized into four emerging themes: 1) limited physical infrastructure for schistosomiasis research and training, 2) a low critical mass of scientists with competencies in schistosomiasis research, 3) a limited scope of current schistosomiasis research, and 4) limited advocacy and community engagement for schistosomiasis control. National and international partnerships, as well as partnerships between academics and implementers, should be harnessed to establish a vibrant network for schistosomiasis research training in resource-limited settings where the disease remains endemic.
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http://dx.doi.org/10.4269/ajtmh.24-0645 | DOI Listing |
Trop Med Health
September 2025
RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
Background: Schistosomiasis is a neglected tropical disease caused by parasitic flatworms of the genus Schistosoma. Currently, praziquantel is the only medication available for treating schistosomiasis. However, crucial issues regarding drug resistance, reinfection, and prevention remain unresolved.
View Article and Find Full Text PDFPLoS Negl Trop Dis
August 2025
The END Fund, New York, United States of America.
Background: Soil-transmitted helminthiasis (STH) and schistosomiasis (SCH) remain significant public health challenges in Rwanda, affecting individuals across all age groups. Despite ongoing mass drug administration (MDA) efforts, updated data on prevalence and risk factors are crucial for effective control and elimination strategies. This study reassessed the prevalence of STH and SCH in both children and adults in Rwanda, along with their associated risk factors, to guide control efforts.
View Article and Find Full Text PDFPLoS Pathog
August 2025
Key Laboratory for Pathogen Infection and Control of Jiangsu Province, Department of Pathogen Biology and Immunology, School of Basic Medical Sciences, National Vaccine Innovation Platform, Nanjing Medical University, Nanjing, Jiangsu, China.
Background: Schistosomiasis is an important neglected tropical disease necessitating focus. Cercarial proteases are essential for schistosome invasion. Leishmanolysin has been identified as the most predominant protease in Schistosoma japonicum (S.
View Article and Find Full Text PDFGigaByte
August 2025
Department of Biology, Royal Museum for Central Africa, Tervuren, Belgium.
Snail-borne parasitic diseases, such as schistosomiasis and fascioliasis, pose significant public health and economic challenges worldwide. Schistosomiasis affects over 250 million people globally, with most cases in sub-Saharan Africa, while fascioliasis contributes substantially to livestock morbidity and economic losses. Freshwater snails (, , and spp.
View Article and Find Full Text PDFParasitol Int
February 2026
Department for Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
This study aimed to determine the human positivity rate for S. mansoni infection and evaluate the association between socioeconomic factors and behavioral factors, as well as identify risk areas and changes in risk factors over the years 2014, 2015, and 2022 in rural communities in Brazil. We conducted three cross-sectional studies, included parasitological and malacological surveys, as well as risk questionnaires.
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