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The aim of the current study was to explore the relationships between 20-meter sprinting time and composite indices of femoral neck strength (compression strength index (CSI), bending strength index (BSI) and impact strength index (ISI)) in a group of middle-aged active men. 50 middle-aged active men voluntarily participated in this study. Their mean age was 45 ± 8.6 years. Body composition, total hip bone mineral density (TH BMD) and femoral neck bone mineral density (FN BMD) were evaluated by DXA. Sprinting time was negatively correlated to CSI (r = -0.52; p < 0.001), BSI (r = -0.43; p < 0.01) and ISI (r = -0.47; p < 0.001). The significant correlations between sprinting time and composite indices of femoral neck strength (CSI, BSI and ISI) remained significant after controlling for body weight, age and maximum oxygen consumption using multiple linear regressions. In conclusion, the current study suggests that sprinting performance (m/sec) is a positive determinant of CSI, BSI and ISI in middle-aged men.
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http://dx.doi.org/10.1016/j.jocd.2025.101586 | DOI Listing |
Aging Cell
September 2025
San Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, California, USA.
Entropy, characterized by increased disorder throughout biological systems, can be quantified by homeostatic dysregulation (HD). One potential measure of HD is the dispersion of points from a normal value, approximated at the individual level by Mahalanobis distance (D). We hypothesized that greater HD in electrocardiogram (ECG) would also reflect greater HD in the musculoskeletal system which, in turn, would be associated with age and manifest as an increased risk of fracture independently of age, bone mineral density (BMD), and history of fracture.
View Article and Find Full Text PDFJ Orthop Sci
September 2025
Department of Orthopaedic Surgery, NHO Saga Hospital, 1-20-1 Hinode, Saga 849-0923, Japan.
Background: Hounsfield units (HU) on computed tomography (CT) are strongly correlated with bone mineral density (BMD) and may aid in osteoporosis screening. However, there is no standardized method for assessing bone density in displaced femoral head fractures. This study aimed to measure HU values in the femoral head using preoperative post-fracture CT images of patients with intertrochanteric femoral fractures and investigate whether it correlated with BMD measured by dual-energy X-ray absorptiometry (DXA).
View Article and Find Full Text PDFAm J Vet Res
September 2025
Division of Surgery, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, Thailand.
Objective: To evaluate the impact of postoperative swimming therapy on hind limb functional recovery in dogs following femoral head and neck excision (FHNE) using the symmetry index (SI) of peak vertical force (PVF) data from ground reaction force measurements and orthopedic evaluations.
Methods: From February 18, 2021, through February 18, 2023, dogs undergoing FHNE were randomized to swimming and nonswimming therapy groups. Hind limb PVF and an orthopedic assessment score were recorded at 1, 2, 3, 4, 5, 6, 9, and 12 months postoperatively.
Endocrine
September 2025
Otorhinolaryngology, Head and Neck Surgery, Candiolo Cancer Institute, FPO-IRCCS Turin, Turin, Italy.
Background: While osteoporosis in primary hyperparathyroidism (PHPT) is widely studied, PHPT patients with osteopenia remain less characterized. This study aimed to evaluate the prevalence, biochemical features, and estimated fracture risk of osteopenic PHPT patients in a real-life cohort.
Methods: We retrospectively analyzed a consecutive series of PHPT patients with available densitometric data at three sites.
Osteoporos Int
September 2025
Department of Rheumatology, First Faculty of Medicine, Charles University, Katerinska 32, Prague, 121 08, Czech Republic.
Unlabelled: REMS-BMD by radiofrequency echographic multispectrometry is primarily determined by a patient's BMI, age, and sex. Only about 2.8% of the changes in femoral neck REMS-BMD can be attributed to replacement of the total hip with metal implants.
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