Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: Childhood and adolescence, as critically important developmental stages, set the premise for the lifelong trajectory of health and well-being. Epidemiologic evidence abounds in purporting that half of all lifetime mental disorders begin in adolescence. Epidemiologic data based on structured clinical diagnostic assessments are disproportionately scarce in Asian countries that host fast-growing youth population along a wide socioeconomic spectrum in the course of globalisation.

Methods: A cross-sectional school-based epidemiologic survey was conducted on a representative random sample of children and adolescents aged 6-17 years from September 2019 to June 2023 in Hong Kong Special Administrative Region (Hong Kong SAR). The main diagnostic measures were 31 DSM-5 disorders assessed with Diagnostic Interview Schedule for Children, Version 5 (DISC-5) on the whole study sample. One parent/caregiver of each participant was interviewed for cases from primary schools. Separate parent/caregiver and student interviews were conducted for cases from secondary schools where research diagnoses derived from both sources in the adolescent/caregiver pair were combined at disorder level. A host of developmental and psychosocial factors were also collected. The study sample was reconstituted according to the discrepancy between the study population and official population data (census mid-year 2022 and Education Bureau) in terms of age, sex, ethnicity, household income and school type to give weight-adjusted prevalence estimation of various disorders.

Findings: The final weighted sample consisted of 6082 participants. The 12-month prevalence of having only one DSM-5 disorder was 13.5% (95% CI: 12.6-14.3%), while the 12-month prevalence of having two or more DSM-5 disorders was 11.0% (95% CI: 10.2-11.8%). The most prevalent disorders/categories of disorders were attention-deficit/hyperactivity disorder (ADHD) (10.2%, 95% CI: 9.4-11.0%); any disruptive, impulse control and conduct disorders (8.8%, CI:8.1-9.5%); any anxiety disorders (6.1%, 95% CI: 5.5-6.7%); any depressive disorders (5.4%, 95% CI: 4.8-6.0%). The 12-month prevalence rates of suicide ideation, plan, and attempt (not including the non-suicidal self-injury) were respectively 3.9% (95% CI: 3.4-4.4%), 1.9% (95% CI: 1.6-2.3%), 1.1% (95% CI: 0.8-1.3%). Parental anxiety and depressive symptoms, any clinically significant sleep disorder, and major school maladjustments (such as repeating a grade, school suspension, absenteeism) were significant factors associated positively (ORs: 1.1-3.37, p-values < 0.01-0.001) with ADHD, externalizing and internalizing disorders in multivariate logistic regressions that account for a multitude of developmental and environmental factors.

Interpretation: This study provides the first comprehensive mental health survey on children and adolescents that might inform other high-income regions in Asia and other robustly thriving economies in the coming decades. The common mental health problems present unmet needs in the school community and yet the related factors are accessible and potentially modifiable. Sustainable mental health initiatives should prioritise an integrated approach to the well-being of parent-child dyad, early detection and intervention targeting sleep disorders, and build a holistic learning support environment in school communities.

Funding: Health and Medical Research Fund, Health Bureau, Hong Kong Special Administrative Region (MHS-P1(Part 1)-CUHK).

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11997334PMC
http://dx.doi.org/10.1016/j.lanwpc.2025.101533DOI Listing

Publication Analysis

Top Keywords

hong kong
16
prevalence dsm-5
12
12-month prevalence
12
mental health
12
disorders
10
mental disorders
8
epidemiologic survey
8
kong sar
8
children adolescents
8
kong special
8

Similar Publications

Background: Experience with icodextrin use in children on long-term peritoneal dialysis is limited. We describe international icodextrin prescription practices and their impact on clinical outcomes: ultrafiltration, blood pressure control, residual kidney function (RKF), technique and patient survival.

Methods: We included patients under 21 years enrolled in the International Pediatric Peritoneal Dialysis Network (IPPN) between 2007 and 2024, on automated PD with a daytime dwell.

View Article and Find Full Text PDF

Quinoline as a Photochemical Toolbox: From Substrate to Catalyst and Beyond.

Acc Chem Res

September 2025

Department of Chemistry, FRQNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke Street W, Montréal, Québec H3A 0B8, Canada.

ConspectusMolecular photochemistry, by harnessing the excited states of organic molecules, provides a platform fundamentally distinct from thermochemistry for generating reactive open-shell or spin-active species under mild conditions. Among its diverse applications, the resurgence of the Minisci-type reaction, a transformation historically reliant on thermally initiated radical conditions, has been fueled by modern photochemical strategies with improved efficiency and selectivity. Consequently, the photochemical Minisci-type reaction ranks among the most enabling methods for C()-H functionalizations of heteroarenes, which are of particular significance in medicinal chemistry for the rapid diversification of bioactive scaffolds.

View Article and Find Full Text PDF

Cancer, with its inherent heterogeneity, is commonly categorized into distinct subtypes based on unique traits, cellular origins, and molecular markers specific to each type. However, current studies primarily rely on complete multi-omics datasets for predicting cancer subtypes, often overlooking predictive performance in cases where some omics data may be missing and neglecting implicit relationships across multiple layers of omics data integration. This paper introduces Multi-Layer Matrix Factorization (MLMF), a novel approach for cancer subtyping that employs multi-omics data clustering.

View Article and Find Full Text PDF

Purpose: The purpose of this study was to determine through a Delphi process a list of outcomes measures for clinicians to use when assessing individuals with Lumbar Spinal Stenosis (LSS).

Methods: A three-phase Delphi process was conducted by the International Society for the Study of the Lumbar Spine (ISSLS) Lumbar Spinal Stenosis Taskforce, including two online surveys, two virtual meetings, and three in-person consensus meetings at the ISSLS annual conferences (2023-2025). Participants evaluated and ranked outcome measures for LSS, with final endorsement requiring > 66% agreement.

View Article and Find Full Text PDF