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http://dx.doi.org/10.1016/j.lana.2025.101073 | DOI Listing |
PLoS Comput Biol
September 2025
Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, United States of America.
Compartmental infectious disease models are used to calculate disease transmission, estimate underlying rates, forecast future burden, and compare benefits across intervention scenarios. These models aggregate individuals into compartments, often stratified by characteristics to represent groups that might be intervention targets or otherwise of particular concern. Ideally, model calculation could occur at the most demanding resolution for the overall analysis, but this may be infeasible due to availability of computational resources or empirical data.
View Article and Find Full Text PDFFront Nutr
August 2025
Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, United States.
Introduction: In Small Island Developing States (SIDS), limited statistical capacity and reliance on imports hinder comprehensive assessments of food systems. For island territories, this issue is more pronounced as food production data are disaggregated, inconsistent, and scarce. Most non-independent territories within the SIDS designation are not included in international food availability datasets, and local datasets are not readily available.
View Article and Find Full Text PDFJ Am Coll Cardiol
September 2025
Division of Research, Kaiser Permanente Northern California, Oakland, California, USA; Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California, USA; Departments of Epidemiology, Biostatistics, and Medicine, University of California-San Franci
Background: Asian American, Native Hawaiian, and Other Pacific Islander (AANHPI) persons comprise ∼10% of the U.S. population-24 million people-yet a significant gap exists in contemporary data on incident heart failure (HF).
View Article and Find Full Text PDFArch Gerontol Geriatr
August 2025
Division of Nephrology, Huashan Hospital, Fudan University, Shanghai, China; National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China. Electronic address:
Background: Chronic kidney disease (CKD) is a major public health challenge for older adults, increasing global healthcare burdens. However, comprehensive global analyses of long-term trends and regional disparities in CKD burden among older adults are still lacking. To fill this critical gap, we aimed to assess global, regional, and national CKD trends and identify age-specific patterns among adults aged ≥60 years.
View Article and Find Full Text PDFFront Pediatr
August 2025
Center for Reproductive Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Background: Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. This study provides a comprehensive analysis of the global burden of CHAs, focusing on sex-stratified trends across Socio-Demographic Index (SDI) quintiles from 1990 to 2021.
Methods: Utilizing data from the Global Burden of Disease (GBD) study, we assessed sex-disaggregated metrics including prevalence, incidence, mortality, disability-adjusted life years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) for CHAs in 21 GBD regions and 204 countries.