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Article Abstract
Objective: The aim was to investigate the paraspecific efficiacy of the National HSGM-polyvalent snake antivenom, which is used in the treatment of snakebite poisoning cases in Turkey, on Vipera ammodytes ammodytes and Vipera berus berus snakes that live widely in Europe and Montivipera raddei venoms that live in Turkey and Armenia.
Method: The paraspecific efficiacy of the antivenom on these three venoms were determined using the test method for neutralization of the lethal effect of the venom in mice specified in the European pharmacopoeia.
Conclusion: It was observed that HSGM-PVSAV produced using Vipera ammodytes montandoni, Macrovipera lebetina obtusa and Montivipera xanthina venoms showed an effect above the European pharmacopoeia limits against all three snake venoms.
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| http://dx.doi.org/10.1016/j.toxicon.2025.108349 | DOI Listing |
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