Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Purpose: To compare outcomes, including complications and admission status of pediatric type I open fractures treated operatively versus nonoperatively, and to expand on a previously published analysis regarding the efficacy and safety of nonoperative treatment of pediatric type I open fractures by this group.

Methods: Retrospective chart review via ICD-9 and ICD-10 codes correlated with type 1 open fractures of long bones at our Level 1 Children's Hospital from 2000 to 2020. Nonoperative management included IV antibiotics and closed reduction and immobilization under sedation. Operative management included formal I&D and ORIF. Demographics, antibiotic administration, hospitalization, and complications were compared using independent t test, and chi-squared or fisher exact test. Radiographic healing was analyzed.

Results: Ninety patients met inclusion criteria [52 nonoperative (NO), 38 operative (OR)] (Table 1). Patients were treated predominately with cefazolin (NO 85.7%, OR 71.4%). Nonoperative patients were more frequently given oral antibiotics (NO 82.7%, OR 44.7%, p value 0.004). Those treated operatively were more frequently admitted (71.1% vs. 25%, p < 0.001). There were three deep infections in the operative cohort requiring repeat operative I&D (p 0.110) (Table 2). There were more incisional infections (7.9% vs. 1.9%), nonunion (2.6% vs. 0%), and ED visits/readmissions (10.5% vs. 3.8%) in the operative cohort. Loss of reduction was more common in the nonoperative cohort (9.6% vs. 5.2%), and refracture/peri-implant fracture in the operative (10.5% vs. 0%). Comparison of overall complications favored the nonoperative group (p = 0.037, Table 3).

Conclusions: Nonoperative management is a safe and effective treatment of pediatric type I open fractures, including decreased hospital admission and elimination of anesthesia risks.

Level Iii Evidence: Retrospective comparative study.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00590-025-04277-6DOI Listing

Publication Analysis

Top Keywords

type open
16
open fractures
16
pediatric type
12
operative management
8
treated operatively
8
management included
8
nonoperative
5
nonoperative versus
4
versus operative
4
management pediatric
4

Similar Publications

The argan tree (Argania spinosa L. Skeels), native to the sub-Saharan region of Morocco, is an endangered agroforestry species renowned for producing one of the world's most expensive and sought-after oils. However, this valuable resource is threatened by the Mediterranean fruit fly (Ceratitis capitata (Wied.

View Article and Find Full Text PDF

Pregnancy loss is a traumatic experience, and the quality of care can vary significantly across healthcare settings. However, evidence on the impact of different types of care on psychological outcomes is limited. This study examined the relationship between specialized care for parents experiencing pregnancy or neonatal loss and the level of Prolonged Grief Disorder (PGD) and Post-Traumatic Stress Disorder (PTSD) symptoms, as well as the role of midwifery support, one month post-loss.

View Article and Find Full Text PDF

We study the elementary problem of moving an active particle by a trap with minimum work input. We show analytically that (open-loop) optimal protocols are not affected by activity, but work fluctuations are always increased. For closed-loop protocols, which rely on initial measurements of the self-propulsion, the average work has a minimum for a finite persistence time.

View Article and Find Full Text PDF

Concomitant Comedications and Survival With First-Line Pembrolizumab in Advanced Non-Small-Cell Lung Cancer.

JAMA Netw Open

September 2025

Oncostat U1018, Institut National de la Santé et de la Recherche Médicale (INSERM), Ligue Contre le Cancer, Paris-Saclay University, Villejuif, France.

Importance: Antibiotics, steroids, and proton pump inhibitors (PPIs) are suspected to decrease the efficacy of immunotherapy.

Objective: To explore the association of comedications with overall survival (OS) in patients with advanced non-small-cell lung cancer (NSCLC).

Design, Setting, And Participants: This nationwide retrospective cohort study used target trial emulations of patients newly diagnosed with NSCLC from January 2015 to December 2022, identified from the French national health care database.

View Article and Find Full Text PDF