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Introduction: Intrauterine devices (IUDs) are effective long-term contraceptives. Although rare, IUD migration can lead to severe complications if undiagnosed. Migration may present with pain, or remain asymptomatic, and unvisualized devices are often presumed expelled without confirmation.
Case Presentation: A 40-year-old African female, Para 2 Living 2, presented with a two-week history of intermittent dull right lower abdominal pain and a history of heavy menstrual bleeding managed with a myomectomy and contraceptive methods. A copper IUD (Cu-IUD) was inserted ten years prior to presentation but presumed expelled after it was not visualized on ultrasound two years later. A year after this, the patient reported that a Mirena IUD had been inserted without complications. One year before the current admission, a CT scan performed elsewhere during evaluation for hip and leg pain incidentally revealed two IUDs within the uterus. She was reassured and took no further action. Current imaging showed a migrated IUD near the urachal ligament and another device correctly positioned in the uterus. The patient underwent exploratory laparotomy to retrieve the migrated IUD and elective hysterectomy for abnormal uterine bleeding. Her postoperative recovery was uneventful.
Discussion: IUD migration, though rare, can cause pain, perforation, and infection. Failure to confirm expulsion may result in undiagnosed complications. This case highlights the importance of clinical suspicion and imaging when an IUD is unvisualized.
Conclusion: Unvisualised IUD warrants thorough evaluation. This case underscores the necessity of confirmatory imaging in cases of unvisualised IUDs to prevent delayed diagnosis and complications.
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http://dx.doi.org/10.1016/j.ijscr.2025.111262 | DOI Listing |
Langmuir
September 2025
Centre for Biomedical Engineering, Indian Institute of Technology, Delhi, New Delhi 110016, India.
The study addresses the critical issue of sepsis diagnosis, a life-threatening condition triggered by the body's immune response to infection that leads to mortality. Current diagnostic methods rely on the time-consuming assessment of multiple biomarkers by a series of tests, leading to delayed treatment. Here, we report a platform for developing a point-of-care (POC) device utilizing electrochemical immunosensors for the dual and rapid detection of sepsis biomarkers: Procalcitonin (PCT), Interleukin-6 (IL-6), and C-reactive protein (CRP) as host markers and lipopolysaccharide (LPS) as a pathogen marker.
View Article and Find Full Text PDFLemierre's syndrome (LS), otherwise known as postanginal sepsis, is a frequently overlooked condition characterized by septic thrombophlebitis of the internal jugular vein (IJV), usually caused by oropharyngeal infection. However, ear space (otogenic) infections are one of the atypical causes of LS and have been rarely reported. We present a case of a male in his 20s with a history of recurrent acute otitis media (RAOM) who presented with purulent ear discharge, fever, neck pain, and swelling for a week.
View Article and Find Full Text PDFNew Microbes New Infect
October 2025
University of Zurich Centre for Travel Medicine, WHO Collaborating Centre for Travellers' Health, Department of Public and Global Health, MilMedBiol Competence Centre, Institute for Epidemiology, Biostatistics and Prevention, University of Zurich, Hirschengraben 84, 8001, Zurich, Switzerland.
Background: In the context of this paper, airport/seaport malaria denotes the accidental relocation by air or sea of a malaria infected mosquito to Europe, a non-endemic area, the survival of the transported mosquito and subsequent blood meal and infection of a local person. Autochthonous malaria refers to locally transmitted cases of malaria in Europe.
Methods: The systematic review followed PRISMA guidelines and was registered on PROSPERO (CRD42023444243).
Urol Case Rep
September 2025
Austin Health, Heidelberg, VIC, Australia.
We report a 43-year-old man with de novo metastatic testicular seminoma complicated by paraplegia from spinal cord compression due to retroperitoneal lymphadenopathy. Urgent retroperitoneal biopsy confirmed seminoma and, after the patient declined neurosurgical intervention, systemic chemotherapy was promptly initiated prior to delayed orchidectomy. Post-chemotherapy orchidectomy histology revealed minimal viable tumour and serial imaging showed a residual retroperitoneal mass with low-grade uptake on FDG-PET.
View Article and Find Full Text PDFCureus
August 2025
Division of Infectious Diseases, Hyogo Prefectural Kobe Children's Hospital, Hyogo, JPN.
Tuberculous meningitis (TBM) is predominantly observed in developing countries but remains relatively rare in developed countries. Therefore, if a clinician does not suspect TBM, its diagnosis may be delayed. Furthermore, drug-induced hepatotoxicity is common and can become severe during TBM treatment.
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