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http://dx.doi.org/10.1111/jgh.16971 | DOI Listing |
J Gastroenterol Hepatol
June 2025
Sharif Medical and Dental College, Lahore, Pakistan.
Spectrochim Acta A Mol Biomol Spectrosc
November 2024
Dipartimento di Medicina Clinica e Sperimentale, Università di Foggia, 71122 Foggia, Italy. Electronic address:
Colorectal cancer is one of the most diagnosed types of cancer in developed countries. Current diagnostic methods are partly dependent on pathologist experience and laboratories instrumentation. In this study, we used Fourier Transform Infrared (FTIR) spectroscopy in transflection mode, combined with Principal Components Analysis followed by Linear Discriminant Analysis (PCA-LDA) and Partial Least Squares - Discriminant Analysis (PLS-DA), to build a classification algorithm to diagnose colon cancer in cell samples, based on absorption spectra measured in two spectral ranges of the mid-infrared spectrum.
View Article and Find Full Text PDFMolecules
September 2023
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123 Palermo, PA, Italy.
The marine environment is an excellent source of molecules that have a wide structural diversity and a variety of biological activities. Many marine natural products (MNPs) have been established as leads for anticancer drug discovery. Most of these compounds are alkaloids, including several chemical subclasses.
View Article and Find Full Text PDFTurk J Gastroenterol
May 2023
Department of Gastroenterology, Ege University Faculty of Medicine, İzmir, Turkey.
Inflammatory bowel diseases are multifactorial, chronic, continuous, relapsing, and immune-mediated diseases of the gastrointestinal tract. It has been believed that mechanisms underlying inflammatory bowel diseases include genetic predisposition, environmental factors, and altered immune response to the gut microbiome. The epigenetic modulation takes place via chromatin modifications, including phosphorylation, acetylation, methylation, sumoylation, and ubiquitination.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
April 2023
Division of Digestive Surgery, Department of Surgery, Udayana University, Prof. I.G.N.G. Ngoerah Hospital, Denpasar, Bali, Indonesia.
Objective: To prove the role of MUC2, MUC13, and NFκB protein expression as significant carcinogenesis pathways in colorectal cancer development.
Methods: This is a nested case-control study conducted at the Udayana University, Sanglah General hospital, from September 2020 to 2021. All eligible subjects who visited the Digestive Surgery outpatient clinic with a colorectal surgery plan 2021 were included.