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http://dx.doi.org/10.1016/j.jchf.2025.01.026 | DOI Listing |
Eur J Heart Fail
September 2025
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, TX, USA.
Aims: Obesity is commonly hypothesized to lead to the development of heart failure (HF) in part due to increases in blood volume (BV) and left ventricular (LV) remodelling. Whether adiposity and obesity severity are associated with BV expansion and subsequent LV remodelling in middle-aged individuals at increased risk (IR) prior to the onset of HF is unknown.
Methods And Results: We analysed data from 96 middle-aged (40-64 years) non-obese (25.
JTCVS Open
August 2025
Department of Cardiothoracic Surgery, University of Louisville and Norton Children's Hospital, Louisville, Ky.
Objectives: Severe obesity is an established risk factor for adverse cardiovascular events and heart transplantation (HT) outcomes in adults. However, the effect of severe obesity on children after HT is not well studied. We aimed to examine the prevalence and effect of severe obesity on pediatric HT.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Obstetrics and Gynecology, Civil Aviation General Hospital, Beijing, China.
This study aims to elucidate the relationship between the triglyceride-glucose index (TyG) index and perimenopausal abnormal uterine bleeding (AUB) risk. A total of 306 patients diagnosed with perimenopausal AUB at our hospital between January 2022 and December 2023 were enrolled. Using a TyG index cutoff of 0.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Chest Diseases, Health Ministry of the Turkish Republic, Bursa City Hospital, Bursa, Türkiye.
Using high-flow nasal cannula (HFNC) in patients with hypoxemic respiratory failure to avoid intubation raises concerns about its potential to increase mortality due to delayed intubation. Identifying at-risk patients is essential. While the literature predicts risk with oxygen-based indices (ROX, SpO2/FiO2, PaO2/FiO2), we aimed to detect ventilation insufficiency.
View Article and Find Full Text PDFJ Intensive Care Med
September 2025
Independent Researcher, Outcomes Research, Atlanta, GA, USA.
Purpose: Obesity is a risk factor for sepsis complications in older adults. We assessed the impact of metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUHO) on outcomes in septic shock.
Methods: We conducted a retrospective analysis using the National Inpatient Sample (2016-2020) to identify a cohort of 1,737,075 patients aged 65 years and older who were hospitalized with septic shock, as defined by ICD-10 diagnosis codes.