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http://dx.doi.org/10.1016/j.abd.2024.11.001 | DOI Listing |
J Infect Public Health
October 2025
Center for Research for Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:
Mpox, caused by the monkeypox virus (MPXV), re-emerged as a significant global health issue in 2024, resulting in the declaration of a second Public Health Emergency of International Concern (PHEIC). The emergence of Clade Ib in Central Africa, particularly affecting children and immunocompromised individuals, and the ongoing global spread of Clade IIb have raised concerns about increased transmissibility and virulence, potentially driven by accelerated APOBEC3-mediated viral mutations. Novel vaccination strategies include the licensed JYNNEOS and Japan's LC16 KMB, as well as promising mRNA vaccine candidates currently in clinical trials.
View Article and Find Full Text PDFPathog Glob Health
August 2025
Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
The mortality trends associated with the mpox virus (MPXV) are not well defined. This study aims to systematically assess the mortality rate of mpox and its stratification across different geographical locations. Comprehensive review of articles from the PubMed, Embase, Scopus, and Web of Science databases up to June 2025, focusing on studies reporting mortality rates among patients diagnosed with mpox.
View Article and Find Full Text PDFMicroorganisms
August 2025
Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021 Bucharest, Romania.
Mpox has become a significant health concern since the global outbreak that began in 2022. The aim of this study is to present the epidemiological situation of Mpox in Romania during 2022-2023 and to describe a severe case of Mpox in a patient who survived despite multiple co-pathologies. Forty-seven confirmed cases were reported at the national level, all in men, in 2022.
View Article and Find Full Text PDFInfect Disord Drug Targets
August 2025
RAK College of Pharmacy, RAK Medical & Health Sciences University, Ras Al Khaimah, United Arab Emirates.
Introduction: Monkeypox (Mpox) is a disease primarily transmitted through direct contact with infected animals and humans. Recently, it has generated worldwide interest due to its expansion from endemic to non-endemic areas, raising concerns about its clinical consequences.
Method: A comprehensive literature review was conducted using PubMed, Scopus, and Web of Science, focusing on clinical data, immune evasion mechanisms, and public health reports related to monkeypox.
Soc Sci Med
August 2025
University of Florida, Gainesville, FL, USA. Electronic address:
Background: Since May 2022, a clade II multinational mpox outbreak has disproportionately affected certain sexually and gender minoritized individuals (SGM). Beyond infectious disease risks, SGM populations face social and structural inequities that may increase their likelihood of experiencing homelessness or engaging in transactional sex (TS). Research on the impact of homelessness and TS on risk of mpox is limited, especially among SGM.
View Article and Find Full Text PDF