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Background: Using nationally representative data from the 2020-2021 Korea National Health and Nutrition Examination Survey, we examined associations between indoor air pollutant exposure and potential obstructive sleep apnea (OSA) risk, estimated by STOP-BANG questionnaire scores.
Methods: We included 1,501 participants who completed the STOP-BANG questionnaire and consented to in-home air quality measurements per Korea's Indoor Air Quality (IAQ) standards. Data were weighted for national representativeness, and multivariate logistic regression models identified determinants of potential OSA risk with adjusted odds ratios and 95% confidence intervals.
Results: From our adjusted model, odds ratios (95% CI) for OSA risk with a unit increase in age were 1.07 (1.05-1.09) for men and 1.04 (1.01-1.07) for women, respectively. The ratios with systolic blood pressure were 1.05 (1.03-1.06) and 1.01 (0.99-1.02), and those with body mass index (BMI, Kg/m) were 1.12 (1.01-1.24) and 1.08 (0.95-1.22) respectively. Unit increase in indoor formaldehyde (HCHO) exposure raised OSA risk by 1.02 (1.00-1.02) fold in men, after controlling for socioeconomic and behavioural factors as well as other common indoor pollutants (CO2, PM2.5 and Toluene) and outdoor PM2.5. No significant association was obtained from women's data.
Conclusions: Our study found a potential association between elevated indoor HCHO levels and increased OSA risk in men. These findings highlight the importance of indoor air quality in OSA prevention, supporting the future development of more effective prevention models and interventions.
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http://dx.doi.org/10.1186/s12889-025-22127-2 | DOI Listing |
Diabetes Metab Syndr Obes
August 2025
Department of Otolaryngology, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, People's Republic of China.
Purpose: Obstructive sleep apnea (OSA) contributes to non-alcoholic fatty liver disease (NAFLD) via pathways involving insulin resistance (IR). The triglyceride-glucose (TyG) index, a widely used marker of IR, is associated with both OSA and NAFLD. However, the role of the TyG index in linking OSA to NAFLD remains underexplored.
View Article and Find Full Text PDFSleep Adv
July 2025
Waisman Center, University of Wisconsin, Madison, Madison, WI 53705, United States.
This study provided a preliminary examination of indices of obstructive sleep apsnea (OSA) and sleep disruptions in adults with Down syndrome (DS), and their associations with Alzheimer's disease (AD) pathology and symptomatology. A total of 93 adults with DS (aged 25-61 years) from the Alzheimer Biomarker Consortium-DS completed cognitive assessments, MRI and positron emission tomography (PET) scans (assessing amyloid-beta [Aβ] and tau), and a one-night home sleep study using the WatchPAT-300 device. Study partners also reported on depressive symptoms and diagnoses.
View Article and Find Full Text PDFJ Obes Metab Syndr
September 2025
Integrated Perioperative Geriatric Excellent Research Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Background: Morbid obesity is a well-established risk factor for cardiovascular disease. Diastolic dysfunction, particularly in non-cardiac surgeries, has been associated with increased incidence of adverse cardiovascular events. This study aimed to evaluate the prevalence of diastolic dysfunction in morbidly obese patients undergoing bariatric surgery and to identify associated clinical risk factors using transesophageal echocardiography (TEE).
View Article and Find Full Text PDFRespir Med
September 2025
Department of Public Health and Infectious Diseases, Pulmonology Unit, Policlinico Umberto I, "Sapienza" University of Rome, 00185 Rome, Italy.
Purpose: Asthma and obstructive sleep apnea (OSA) are two respiratory diseases that often may coexist, resulting in Alternative Overlap Syndrome (aOVS), which is still underestimated and underdiagnosed.
Objectives: This state-of-art review aims to describe the current evidence on aOVS, including its pathophysiology, clinical, functional and therapeutic implications. A secondary objective is to assess whether aOVS can be identified as a distinct endophenotype needing personalized diagnostic and therapeutic strategies.
Br J Anaesth
September 2025
Department of Anaesthesia and Pain Management, Perth Children's Hospital, Perth, WA, Australia; Division of Emergency Medicine, Anaesthesia and Pain Medicine, The University of Western Australia, Perth, WA, Australia; Institute for Paediatric Perioperative Excellence, The University of Western Austr
Background: Obstructive sleep apnoea (OSA) has been thought to increase the risk of respiratory depression from opioids. The primary aim of this study was to assess whether preoperative hypoxaemia by sleep study pulse oximetry imparts greater opioid sensitivity.
Methods: A multicentre observational cohort study with in-cohort dose randomisation was performed in children 2-8 yr of age with OSA undergoing adenotonsillectomy.