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http://dx.doi.org/10.1017/ice.2025.55 | DOI Listing |
Int J Infect Dis
September 2025
Department of Laboratory Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China. Electronic address:
Prototheca, a genus of opportunistic pathogenic microalgae, can cause protothecosis in humans and animals, manifesting as cutaneous lesions or disseminated/systemic infections. This report describes a rare case of Prototheca wickerhamii toe infection in a 78-year-old Chinese male, presenting initially as gouty arthritis. The patient, who worked in fish farming with frequent water exposure, had a history of herpes zoster and hypertension.
View Article and Find Full Text PDFVascul Pharmacol
September 2025
Department of Orthopaedic Surgery, Orthopaedic Hospital Research Center, UCLA, Los Angeles, CA 90095, USA; Center for Cardiovascular Science, University of Edinburgh, Edinburgh, UK. Electronic address:
The walls of all embryonic, foetal, and adult blood vessels contain mesodermal progenitors, distributed as pericytes in capillaries and micro vessels, and fibroblastic cells in the tunica adventitia of larger veins and arteries. Following dissociation, selection by flow cytometry, and culture, those perivascular cells turn into bona fide mesenchymal stem cells of which they possess all attributes. In vivo, the adventitial cellular niche supports several spatially-organized subsets of mesodermal progenitors biased toward either osteo-, adipo-, or fibrogenesis, and dominated by more primitive, multi-lineage stem-like cells.
View Article and Find Full Text PDFLancet
September 2025
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool. Electronic address:
Enteric fever, caused by the human-restricted bacteria Salmonella enterica serovar Typhi (typhoid) and Salmonella enterica serovar Paratyphi A, B, and C (paratyphoid), affects persons residing in, or travelling from, areas lacking safe water, sanitation, and hygiene infrastructure. Transmission is by the faecal-oral route. A gradual fever onset over 3-7 days with malaise, headache, and myalgia is typical.
View Article and Find Full Text PDFBioorg Chem
September 2025
Department of Chemistry, Pondicherry University, Kalapet, Puducherry 605014, India. Electronic address:
Malaria, a protozoan parasitic disease caused by Plasmodium species, poses significant health risks in endemic regions and contributes to substantial morbidity and mortality. The intricate lifecycle of the parasite, coupled with the emergence of drug-resistant strains, has severely impacted the effectiveness of current anti-malarial treatments. In response, the present study attempts to demonstrate the blood-stage anti-plasmodial action of 30 triazole derivatives designed based on molecular hybridisation technique, and physicochemical properties.
View Article and Find Full Text PDFKlin Mikrobiol Infekc Lek
June 2025
Clinic of Infectious Diseases, Central Military Hospital, Prague, Czech Republic, e-mail:
Objective: To evaluate the quality of care provided to patients with febrile neutropenia (FN) hospitalized at the Depart-ment of Infectious Diseases, Military University Hospital Prague, as a foundation for improving the management of this condition.
Material And Methods: A retrospective observational analysis of patients diagnosed with the ICD-10 code D70 from 1 January 2015 to 1 June 2023. All evaluated parameters were selected primarily to facilitate the assessment of care quality and compliance with recommended practices.