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We recommend that even in old patients with severe COPD, who could not tolerate chemical pleurodesis, pleurodesis with 50% dextrose should be considered since it is a relatively safe and efficient method.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973728 | PMC |
http://dx.doi.org/10.1002/rcr2.70174 | DOI Listing |
J Investig Med High Impact Case Rep
September 2025
Department of Thoracic and Cardiovascular Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
I report 2 cases of pleurodesis with 50% dextrose water (DW) in very elderly patients with secondary spontaneous pneumothorax. In both cases, a chest computed tomography scan showed a large pneumothorax with emphysema and multiple bullae. Patients were expected not to tolerate surgical treatment, considering their old age and underlying pulmonary disease.
View Article and Find Full Text PDFBMC Cancer
July 2025
Evidence-Based Medicine Center, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, China.
Background: Mannatide is an alpha-hemolytic streptococci bio-product. We conducted a comprehensive clustered systematic review and meta-analysis to reveal the clinical values of Mannatide for controlling malignant pleural effusion (MPE), identify the optimal therapeutic regimens, indications and usage, and assess their clinical effectiveness and safety.
Methods: We collected all eligible studies from both Chinese and English databases and clustered them into homogeneous comparisons or therapeutic regimens.
J Thorac Dis
April 2025
Department of Surgery, Maxima Medical Center, Veldhoven, The Netherlands.
Background: The optimal timing of postoperative chest tube removal remains disputable. Traditionally, chest tubes are left in place for several days for adequate pleurodesis and recurrence prevention after surgery for primary spontaneous pneumothorax (PSP). Currently, early tube removal, defined as immediate removal upon cessation of air leakage, is increasingly practiced.
View Article and Find Full Text PDFGen Thorac Cardiovasc Surg
May 2025
Department of Thoracic Surgery, University of Toyama, 2630 Sugitani, Toyama, Toyama, 930-0194, Japan.
Objective: This study aimed to evaluate the efficacy of thoracoscopic ligation for secondary spontaneous pneumothorax performed via an extrathoracic looping technique in patients with smoking-induced emphysema.
Methods: We retrospectively analyzed clinical data of 58 patients with secondary spontaneous pneumothorax who had histories of smoking and emphysematous lung changes on chest computed tomography. These patients underwent thoracoscopic surgery at our institute between April 2016 and March 2023.
Front Pharmacol
April 2025
Department of Oncology, Lishui People's Hospital, Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang, China.
Introduction: () preparations are widely used to control malignant pleural effusion (MPE) through intrapleural perfusion.
Objectives: This analysis aims to verify the therapeutic values of perfusion with preparations for controlling MPE, reveal the optimal treatment plan, suitable population, and usage, and to demonstrate their clinical effectiveness and safety.
Methods: We performed and reported this systematic review/meta-analysis (PROSPERO: CRD42023430139) following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.