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http://dx.doi.org/10.1080/15265161.2025.2470655 | DOI Listing |
ACS Appl Bio Mater
September 2025
School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
The generation of reactive oxygen species (ROS) through nanozyme-mediated sonocatalytic therapy has demonstrated remarkable therapeutic efficacy in the field of cancer. Nevertheless, it remains a significant challenge for nanozymes with a single catalytic active center to generate sufficient ROS via Fenton or Fenton-like reactions to effectively induce tumor cell death. In order to enhance the catalytic efficacy, we devised and synthesized a multiple active centre and mitochondrial-targeted perovskite nanozyme (NCFP), doped with cobalt (Co) element, and incorporated 4-carboxybutyltriphenylphosphonium bromide (TPP) as a mitochondrial targeting marker for ultrasound (US)-assisted enzyme-like catalytic treatment of tumors.
View Article and Find Full Text PDFJ Phys Chem Lett
September 2025
College of Materials Science and Engineering, Sichuan University, No. 24 South Section 1, Yihuan Road, Chengdu 610065, P. R. China.
Aqueous zinc-ion microbatteries exhibit promising prospects for wearable devices due to their high safety and cost-effectiveness but face challenges such as low energy density and short cycle life. To address these challenges, a dual-plating flexible Zn-Br microbattery was developed using freestanding MXene films as a zinc metal free anode. The MXene anode retains no redundant Zn, as Zn from the electrolyte undergoes deposition/stripping reactions on its substrate, thereby eliminating the necessity for excess zinc.
View Article and Find Full Text PDFJMIR Med Inform
September 2025
Departments of Radiology, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, Guangdong, 510630, China, 86 18922109279, 86 20852523108.
Background: Despite the Coronary Artery Reporting and Data System (CAD-RADS) providing a standardized approach, radiologists continue to favor free-text reports. This preference creates significant challenges for data extraction and analysis in longitudinal studies, potentially limiting large-scale research and quality assessment initiatives.
Objective: To evaluate the ability of the generative pre-trained transformer (GPT)-4o model to convert real-world coronary computed tomography angiography (CCTA) free-text reports into structured data and automatically identify CAD-RADS categories and P categories.
J Med Internet Res
September 2025
School of Advertising, Marketing and Public Relations, Faculty of Business and Law, Queensland University of Technology, Brisbane, Australia.
Background: Labor shortages in health care pose significant challenges to sustaining high-quality care for people with intellectual disabilities. Social robots show promise in supporting both people with intellectual disabilities and their health care professionals; yet, few are fully developed and embedded in productive care environments. Implementation of such technologies is inherently complex, requiring careful examination of facilitators and barriers influencing sustained use.
View Article and Find Full Text PDFJMIR Rehabil Assist Technol
September 2025
Department of Computer Science, Faculty of Technology, Art and Design, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Background: Over the past decade, the proportion of the world's population aged ≥65 years has grown exponentially, presenting significant challenges, such as social isolation and loneliness among this population. Assistive technologies have shown potential in enhancing the quality of life for older adults by improving their physical, cognitive, and communication abilities. Research has shown that smart televisions are user-friendly and commonly used among older adults.
View Article and Find Full Text PDF