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Purpose: Mangled hands refer to disfiguring severe injuries that affect many anatomical components. These injuries are evaluated using various scoring systems. In addition to these ratings, we need to include critical aspects relating to the patient, such as the trauma origin, prognosis, and procedure. We examined the significance of accident etiology in assessing trauma and predicting outcomes, as well as their value in guiding decisions for trauma treatment.
Methods: Thirty-one patients, from 6 to 73 years, have been treated for upper limb compound injuries at our hospital between 2004 and 2009. We registered 10 blast injuries, 10 work accidents, six motor vehicle accidents, and five gunshot injuries. The severity, anatomy, topography, and type assessment method was used to evaluate the prognosis on viability and functionality. Additionally, we studied the influence of the etiological factor on injury prognosis. The functional results have been assessed by the manual muscle testing grading system, whereas the results of the limb usefulness have been evaluated by Disabilities of Arm, Shoulder and Hand (DASH) score test (patients' self-questionnaire).
Results: Seventeen cases involved major vascular lesions that required emergency reconstruction or amputation. Our findings indicate that cases with blast injuries managed by partial or total amputations or using flaps to close stumps had poor prognoses. For cases with work-related injuries, we performed revascularization or flaps where the likelihood of saving the limbs was deemed higher than the potential risks of postoperative complications. In cases with gunshot injuries, despite the low overall functioning seen, our primary approach was to repair rather than amputating because of the potential feasibility of achieving viability.
Conclusions: Further investigation is needed to determine if the cause of trauma has an important impact on trauma evaluation scores and predicting trauma outcomes, furthermore, helping decision making in emergencies.
Type Of Study/level Of Evidence: Prognosis IIa.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11962906 | PMC |
http://dx.doi.org/10.1016/j.jhsg.2024.06.014 | DOI Listing |
Int J Orthop Trauma Nurs
August 2025
Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran. Electronic address:
Background: Knee osteoarthritis (KOA) is a prevalent degenerative joint disorder that significantly impairs physical function and daily activities. While conventional treatments focus on symptom management, complementary therapies such as aromatherapy massage have gained attention for their potential benefits.
Objective: This study evaluates the effects of peppermint oil aromatherapy massage on functional impairments in KOA patients.
Am J Emerg Med
September 2025
Department of Surgical Education, Orlando Regional Medical Center, Orlando, FL, USA; Department of Surgery, Division of Trauma and Surgical Critical Care, Orlando Regional Medical Center, Orlando, FL, USA. Electronic address:
Background: There is conflicting literature regarding mortality outcomes associated with REBOA usage in patients with severe thoracic or abdominal trauma. Our study aims to assess the benefits and negative implications of REBOA use in adult trauma patients in hemorrhagic shock with severe thoracic or abdominal injuries.
Methods: This retrospective cohort analysis utilized the American College of Surgeons Trauma Quality Improvement Program Participant Use File (ACS-TQIP-PUF) database from 2017 to 2023 to evaluate adult patients with severe isolated thoracic or abdominal trauma undergoing REBOA placement.
ACS Nano
September 2025
International School of Microelectronics, Dongguan University of Technology, Dongguan 523808, China.
Mimicking human brain functionalities with neuromorphic devices represents a pivotal breakthrough in developing bioinspired electronic systems. The human somatosensory system provides critical environmental information and facilitates responses to harmful stimuli, endowing us with good adaptive capabilities. However, current sensing technologies often struggle with insufficient sensitivity, dynamic response, and integration challenges.
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September 2025
School of Pharmaceutical Science, Yunnan Key Laboratory of Pharmacology for Natural Products/College of Modern Biomedical Industry, NHC Key Laboratory of Drug Addiction Medicine, Kunming Medical University, Kunming, P. R. China.
20(R)-ginsenoside Rg3 can reduce the effects of oxidative stress and cell death in cerebral ischemia‒reperfusion injury (CIRI). Neuroinflammation is crucial post-CIRI, but how 20(R)-Rg3 affects ischemia‒reperfusion-induced neuroinflammation is unclear. To study 20(R)-Rg3's effects on neuroinflammation and neuronal preservation in stroke models and explore toll-like receptor 4/myeloid differentiation factor-88/nuclear factor kappa B (TLR4/MyD88/NF-κB) pathway mechanisms.
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