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Endoscopic intraperitoneal subserosal dissection (EISD) has been reported to be a promising modified tunneling technique for gastric submucosal tumors (SMTs) with a predominantly extraluminal growth pattern. We evaluated the safety and efficacy of EISD for gastric extraluminal SMTs.We prospectively enrolled consecutive patients who underwent EISD for gastric extraluminal SMTs between October 2018 and March 2024. Clinicopathological characteristics and procedure-related parameters were analyzed.10 patients with 11 gastric extraluminal SMTs were included. The mean (SD) longest and shortest specimen diameters were 2.1 (0.9) cm (range 0.5-4.0) and 1.8 (0.7) cm (range 0.4-3.0), respectively. All SMTs (100%) were resected en bloc, and 10 (90.9%) were retrieved en bloc. The mean (SD) resection and suture times were 58.9 (31.5) minutes (range 26-125) and 12.4 (10.1) minutes (range 3-25), respectively. Two patients experienced type I mucosal injury at the tumor site, and no major adverse events occurred. The mean postoperative hospital stay was 3.4 (SD 0.8) days (range 3-5). No recurrence or metastasis occurred during a mean follow-up period of 32.1 (SD 18.8) months (range 7-71).EISD appeared to be a feasible and safe method for removing gastric extraluminal SMTs in selected patients.
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http://dx.doi.org/10.1055/a-2573-9069 | DOI Listing |
Endosc Int Open
August 2025
Endoscopy Center and Edoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Background And Study Aims: Endoscopic resection for duodenal gastrointestinal stromal tumors (GISTs) is still considered a great challenge with a high risk of complications. This study aimed to evaluate effectiveness and safety of endoscopic resection for duodenal GIST.
Patients And Methods: Between June 2013 and August 2024, we performed a retrospective study of patients with duodenal GISTs who underwent endoscopic resection at Zhongshan Hospital.
Surg Endosc
August 2025
Department of Gastroenterology, Changshu Hospital Affiliated to Soochow University, Suzhou, China.
Background: Endoscopic resection (ER) is a minimally invasive treatment for gastric gastrointestinal stromal tumors (gGISTs), but intraoperative perforation risk remains a significant concern. Currently, no validated tools exist to preoperatively identify high-risk patients. This study aimed to develop and validate a practical scoring system for predicting intraoperative perforation during ER of gGISTs.
View Article and Find Full Text PDFOxf Med Case Reports
July 2025
Medcare Dr. Saeed Al-Shaikh Gastroenterology and Obesity Centre, Sheikh Zayed Road, SMJ Building, PO Box 215565, Dubai, United Arab Emirates.
Large extraluminal gastrointestinal stromal tumours (GISTs) are rare, with varied presentations and patient profiles. This report discusses the case of a 22-year-old female presenting with a 4-month history of lower abdominal pain, weight loss, and recurrent urinary tract infections. Imaging revealed a large intra-abdominal mass (9.
View Article and Find Full Text PDFWorld J Gastrointest Surg
June 2025
Department of Endoscopy, General Hospital of Northern Theater Command, Shenyang 110840, Liaoning Province, China.
Background: Gastric subepithelial lesions (SELs) are elevated lesions originating from the muscularis mucosa, submucosa, or muscularis propria, and may also include extraluminal lesions. For small SELs (less than 5 cm), complete endoscopic excision is the preferred treatment. Endoscopic full-thickness resection (EFTR) has proven to be an effective approach.
View Article and Find Full Text PDFSurg Endosc
July 2025
Department of General, Visceral and Vascular Surgery, Helios Klinikum Pforzheim, Pforzheim, Germany.
Background: Pancreatic anastomosis is a critical step in partial pancreatoduodenectomy, as failure of the anastomosis with postoperative pancreatic fistula can lead to high morbidity and mortality. While various fibrin-based sealing agents have been tested, their effectiveness is limited due to rapid degradation by pancreatic secretions. This study aimed to evaluate the applicability and biocompatibility of a novel biodegradable, polyurethane-based adhesive (VIVO 120™) for intraoperative sealing of pancreatic anastomoses in a long-term survival pig model.
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