Clinical study of real-time three-dimensional echocardiography combined with radionuclide imaging to evaluate changes in cardiac function and synchronization before and after cardiac rehabilitation in patients with acute myocardial infarction.

Objective: This research aimed to unveil the effects of real-time three-dimensional echocardiography (RT-3DE) combined with radionuclide imaging to evaluate changes in cardiac function and synchronization before and after cardiac rehabilitation in patients with acute myocardial infarction (AMI).

Methods: RT-3DE and radionuclide imaging were performed after PCI (pre-rehabilitation) and the 8-week follow-up visit (post-rehabilitation). Relevant data were collected: heart rate (HR), left ventricular (LV) end-systolic volume (LVESV), LV end-diastolic volume (LVEDV), LV ejection fraction (LVEF), LV 16-segment maximum difference in time to minimum systolic volume (Tmsv-16-Dif), LV 16-segment standard deviation of time to minimum systolic volume (Tmsv-16-SD), Tmsv 16-Dif % and Tmsv 16-SD %, summed Stress Score (SSS), Summed Rest Score (SRS), and SDS (SRS-SSS).

Results: At the 8-week follow-up after PCI, HR, LVEDV, LVESV, Tmsv-16-Dif, Tmsv-16-SD, Tmsv-16-Dif%, Tmsv-16-SD%, SSS, SRS, and SDS in the rehabilitation group were lower than those in the control group; LVEF in the rehabilitation group was higher than the control group.

Conclusion: RT-3DE and radionuclide imaging can be used as a follow-up tool for evaluating LV function and synchronization changes after cardiac rehabilitation in patients with AMI undergoing PCI.