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Article Abstract
A 66-year-old man presented with a pedunculated papule measuring 9.0 mm in the left inguinal region. Excision was performed based on the clinical hypotheses of soft fibroma and pyogenic granuloma. Histopathologic evaluation demonstrated invagination of the epidermis, with a tubular tortuous path showing the presence of squamous cells and goblet cells rich in mucin, and adjacent epithelium showing acanthosis, papillomatosis, and hyperkeratosis, with a diagnosis of mucinous syringometaplasia. This is a rare entity, with 19 cases reported to date, including the present case, usually clinically diagnosed as a viral wart or basal cell carcinoma, with no cases of recurrence reported after complete excision.
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Article Synopsis
- A new case of syringometaplasia was reported in a female newborn with a cutaneous defect, which showed unusual metaplastic changes in the eccrine ducts and glands.
- The excision of an enlarging plaque revealed superficial scarring, loss of hair follicles, and abnormal growth of eccrine glands with a unique arrangement of epithelial cells.
- This previously unreported variant has been named ciliated and mucinous adenomatous syringometaplasia, potentially providing insights into the development of certain skin cysts.