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We describe a rare case of a developmental venous anomaly associated with an arteriovenous malformation. A 20-year-old male presented with seizures and was diagnosed with left parietal arteriovenous malformation combined with developmental venous anomaly in the left frontal lobe, with the draining veins of both lesions converging into the same bridging vein despite the lesions affecting anatomically distinct areas. The patient underwent a craniotomy for resection of the arteriovenous malformation. However, progressive aphasia developed on the third postoperative day. Subsequent neuroimaging (CT and MRI) revealed thrombosis formation within the drainage vein of the developmental venous anomaly. The symptoms of aphasia gradually disappeared after anticoagulant therapy with low molecular weight heparin. This case adds to the current consensus that developmental venous anomalies have normal venous drainage. It also suggests that developmental venous anomalies are susceptible to hemodynamic changes.
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http://dx.doi.org/10.3389/fsurg.2025.1562013 | DOI Listing |
Anat Cell Biol
September 2025
Department of Anatomy, All India Institute of Medical Sciences Bibinagar, Hyderabad, India.
We present a rare anatomical variation of the deep femoral vein (DFV) originating from the popliteal vein (PV) with an associated aneurysm. The DFV arose from the PV at the adductor hiatus, exhibited an aneurysm, and coursed upward through the fourth osseo-aponeurotic opening of the adductor magnus muscle to enter the anterior thigh compartment before draining into the femoral vein. This unique variation likely resulted from developmental deviations during intrauterine life.
View Article and Find Full Text PDFNeurol Sci
September 2025
Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Background: Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant disorder characterized by abnormal vascular formations across multiple organ systems, including the brain. While arteriovenous malformations (AVMs) are well recognized in HHT, non-AVM cerebrovascular malformations remain underreported and poorly understood manifestations of the disease.
Methods: A systematic review was conducted using multiple databases, applying a two-step screening process to exclude studies with insufficient, irrelevant, or incomplete data.
Hum Brain Mapp
September 2025
Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Perinatal stroke is a vascular injury occurring early in life, often resulting in motor deficits (hemiplegic cerebral palsy/HCP). Comorbidities may also include poor neuropsychological outcomes, such as deficits in memory. Previous studies have used resting state functional MRI (fMRI) to demonstrate that functional connectivity (FC) within hippocampal circuits is associated with memory function in typically developing controls (TDC) and in adults after stroke, but this is unexplored in perinatal stroke.
View Article and Find Full Text PDFVascul Pharmacol
September 2025
Department of Orthopaedic Surgery, Orthopaedic Hospital Research Center, UCLA, Los Angeles, CA 90095, USA; Center for Cardiovascular Science, University of Edinburgh, Edinburgh, UK. Electronic address:
The walls of all embryonic, foetal, and adult blood vessels contain mesodermal progenitors, distributed as pericytes in capillaries and micro vessels, and fibroblastic cells in the tunica adventitia of larger veins and arteries. Following dissociation, selection by flow cytometry, and culture, those perivascular cells turn into bona fide mesenchymal stem cells of which they possess all attributes. In vivo, the adventitial cellular niche supports several spatially-organized subsets of mesodermal progenitors biased toward either osteo-, adipo-, or fibrogenesis, and dominated by more primitive, multi-lineage stem-like cells.
View Article and Find Full Text PDFClin Anat
September 2025
Department of Anatomy, Faculty of Science, Mahidol University, Bangkok, Thailand.
The postglenoid foramen (PGF) is a rarely reported anatomical variant of the temporal bone, with limited data on its morphology, prevalence, and clinical relevance, particularly in non-European populations. This study aimed to investigate the anatomy and frequency of foramina located on the squamous part of the temporal bone, including the PGF, and to propose a classification system based on their anatomical positions. A total of 117 human skulls (234 sides), including both dried and Thiel-embalmed specimens, were examined through gross observation, cadaveric dissection, and computed tomography (CT) in selected cases.
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