Artificial intelligence automation of echocardiographic measurements.

Background: Accurate measurement of echocardiographic parameters is crucial for the diagnosis of cardiovascular disease and tracking of change over time, however manual assessment is time-consuming and can be imprecise. Artificial intelligence (AI) has the potential to reduce clinician burden by automating the time-intensive task of comprehensive measurement of echocardiographic parameters.

Methods: We developed and validated open-sourced deep learning semantic segmentation models for the automated measurement of 18 anatomic and Doppler measurements in echocardiography. The outputs of segmentation models were compared to sonographer measurements from two institutions to access accuracy and precision.

Results: We utilized 877,983 echocardiographic measurements from 155,215 studies from Cedars-Sinai Medical Center (CSMC) to develop EchoNet-Measurements, an open-source deep learning model for echocardiographic annotation. The models demonstrated a good correlation when compared with sonographer measurements from held-out data from CSMC and an independent external validation dataset from Stanford Healthcare (SHC). Measurements across all nine B-mode and nine Doppler measurements had high accuracy (an overall R of 0.967 (0.965 - 0.970) in the held-out CSMC dataset and 0.987 (0.984 - 0.989) in the SHC dataset). When evaluated end-to-end on a temporally distinct 2,103 studies at CSMC, EchoNet-Measurements performed well an overall R2 of 0.981 (0.976 - 0.984). Performance was consistent across patient characteristics including sex and atrial fibrillation status.

Conclusion: EchoNet-Measurement achieves high accuracy in automated echocardiographic measurement that is comparable to expert sonographers. This open-source model provides the foundation for future developments in AI applied to echocardiography.