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http://dx.doi.org/10.1007/s12928-025-01120-x | DOI Listing |
ACG Case Rep J
October 2024
Department of Medicine, Division of Gastroenterology and Hepatology, University of Maryland Medical System, Baltimore, MD.
Tofacitinib is a Janus kinase inhibitor commonly used in the management of rheumatoid arthritis and moderate-to-severe ulcerative colitis. Anemia is a rare side effect of this medication often with minimal changes in hemoglobin levels. We report the first case of autoimmune hemolytic anemia from tofacitinib use in a patient with inflammatory bowel disease.
View Article and Find Full Text PDFInjury
August 2025
Monash University, Faculty of Medicine, Nursing and Health Sciences, Monash, Victoria 3800, Australia; Department of Plastic and Reconstructive Surgery, Peninsula Health, Melbourne, Victoria 3199, Australia.
Background: Urban expansion into natural habitats has increased human interactions with wild terrestrial and aquatic species, leading to a rise in animal-related injuries. These incidents often result in complex infections, posing major public health challenges. This study examines the epidemiology, therapeutic interventions, and clinical outcomes of infections from non-domesticated animal injuries in the Mornington Peninsula, Australia.
View Article and Find Full Text PDFBlood Transfus
August 2025
Department of Pathology, University of Virginia, Charlottesville, VA, United States of America.
Ann Med Surg (Lond)
September 2025
Department of Internal Medicine, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal.
Introduction And Importance: Systemic sclerosis (SSc) is a rare autoimmune disease characterized by fibrosis of internal organs and vasculopathy. It commonly involves the skin and multiple organs, including the kidneys and cardiovascular system. Cardiac tamponade in SSc is an uncommon manifestation, often occurring alongside scleroderma renal crisis (SRC).
View Article and Find Full Text PDFMol Genet Metab
August 2025
Department of Molecular and Human Genetics, Baylor Coll. of Medicine, Houston, TX, United States; Texas Children's Hospital, Houston, TX, United States; Baylor Genetics, Houston, TX, United States; Joint BCM-CUHK Center of Medical Genetics, Prince of Wales Hospital, ShaTin, Hong Kong, China. Electro
Triosephosphate isomerase (TPI) is a ubiquitously expressed enzyme encoded by the TPI1 gene. It catalyzes the interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in the fifth step of glycolysis. TPI deficiency (TPI Df; MIM# 615512) is an autosomal recessive disorder due to biallelic pathogenic variants in TPI1.
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