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Objectives: Schizophrenia is a chronic condition that requires long-term management. Quality of life is an important outcome measure for individuals diagnosed with schizophrenia; it can be tracked over time allowing evaluation of whether interventions lead to sustainable improvements. Nutrition and dietary interventions are an underutilized treatment for tackling the metabolic consequences of mental illness, which is now recognized as having increased importance in the management of schizophrenia. This study examines the impact of nutrition and dietary interventions on quality of life outcomes for those with schizophrenia.
Methods: A systematic review of the literature was conducted, assessing the impact of nutritional interventions on quality of life outcomes in individuals with a diagnosis of schizophrenia.
Results: A total of 982 articles were screened, of which nine articles met the inclusion criteria. Quality of life measures varied across studies, which made comparison across studies challenging. Previous studies had relatively small sample sizes and did not have long follow-up durations. Some of the studies found that dietary interventions such as counselling, weight management programs, food diaries and nutritional education improved quality of life, whereas others did not detect any effect.
Conclusions: The review provides preliminary evidence that nutrition and dietary interventions may benefit quality of life among individuals with schizophrenia. There were however substantial limitations in studies highlighting the need for further research. The paper also highlights the need to standardize assessment tools for future quality-of-life research.
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http://dx.doi.org/10.1017/ipm.2025.3 | DOI Listing |
Talanta
September 2025
Department of Chemistry, Faculty of Mathematics and Natural Sciences, University of Oslo, 0371, Oslo, Norway; Hybrid Technology Hub - Centre of Excellence, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0315, Oslo, Norway. Electronic address:
Dried blood spots (DBS) offer a practical and relatively non-invasive method for sample collection. Here, we evaluate the feasibility of applying H NMR spectroscopy to metabolomic analysis of DBS. Various solvent suppression techniques and extraction protocols were tested using aqueous and methanolic solvents.
View Article and Find Full Text PDFTalanta
September 2025
Glyn O. Phillips Hydrocolloid Research Centre, National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering of Ministry of Education, Key Laboratory of Industrial Microbiology in Hubei Province, School of Life and Health Sciences, Hubei Univer
Given rising consumer demands for meat safety and quality assurance, developing an intuitive, cost-effective, and user-friendly sensor platform for real-time monitoring of perishable meat freshness is important. Herein, this study developed an innovative chitosan/agarose/blueberry anthocyanin (CS/AG/BA) hydrogel label system for visual real-time freshness tracking of perishable proteins through smartphone-assisted colorimetric analysis. Through systematic optimization of CS/AG compositional ratios (3:7-7:3) and pH conditions (2.
View Article and Find Full Text PDFJ Chromatogr A
September 2025
Luoyang R&D Center of Technology, SINOPEC Engineering (Group) Co., Ltd, Luoyang 471003, China. Electronic address:
Conventional one-dimensional gas chromatography methods for gasoline quality monitoring require separate analyses for different component classes, limiting analytical efficiency and unconventional additive detection. This study presents a comprehensive two-dimensional gas chromatography with flame ionization detection (GC × GC-FID) platform enabling simultaneous quantification of regulated components and rapid screening of unconventional additives in a single analytical run. The method achieved excellent agreement with ASTM standards and high repeatability for BTEX (benzene, toluene, ethylbenzene, and xylenes) and oxygenates in gasoline.
View Article and Find Full Text PDFExpert Opin Investig Drugs
September 2025
Heart Failure Clinic, Division of Cardiology, Alessandro Manzoni Hospital, ASST Lecco, Lecco, Italy.
Introduction: Ischemic heart disease (IHD) constitutes the most prevalent form of cardiac disease in the general population. Although current therapeutic interventions have significantly improved both quality of life and survival rates, no available treatment can reverse the loss of cardiomyocytes resulting from ischemic injury. Existing therapies are limited to attenuating myocardial damage, reducing its extent, and mitigating its clinical consequences.
View Article and Find Full Text PDFHum Cell
September 2025
Eye Hospital, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Age-related eye diseases (AREDs) are the leading cause of visual impairment in the elderly, affecting the structure of the anterior and posterior segments of the eye, significantly reducing the quality of life of patients, and even leading to irreversible blindness. Typical AREDs include age-related cataract (ARC), dry eye disease (DED), age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy (DR), the global prevalence of which continues to rise, becoming a serious public health concern. SIRT1 is an NAD + dependent deacetylase, which plays an important physiological regulatory role in ocular tissues, mainly affecting gene expression and various cellular processes by regulating the acetylation status of substrate proteins.
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