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Higher education is essential because it exposes students to a variety of areas. The academic performance of IT students is crucial and might fail if it isn't documented to identify the features influencing them, as well as their strengths and shortcomings. The student academic prediction system needs to be enhanced so that teachers can forecast their students' performance. Numerous studies have been conducted to increase the prediction accuracy of IT students, but they encountered difficulties with unbalanced data and algorithm tuning. To address these issues, the study proposed different machine learning (ML) algorithms that handled imbalanced data by applying the synthetic minority oversampling technique (SMOTE) and employing hyperparameter tuning algorithms to enhance prediction during the training process. The ML models we used were decision tree (DT), k-nearest neighbor, and XGBoost. The models were fine-tuned by applying Ant colony optimization (ACO) and artificial bee colony optimization techniques. Subsequently, these optimization techniques further enhanced the performance of the models. After comparing them, the results showed that SMOTE and ACO combined with the DT model outperformed other models for academic prediction. Additionally, the study utilized the Kendall Tau correlation coefficient technique to analyze the correlation between features and identify factors that positively or negatively impact student success.
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http://dx.doi.org/10.1038/s41598-025-94642-6 | DOI Listing |
Microb Drug Resist
September 2025
Drug Discovery Research, Wockhardt Research Centre, Wockhardt Ltd., Chhatrapati Sambhajinagar, India.
Cefepime (FEP), a fourth-generation cephalosporin combined with tazobactam (TAZ), a β-lactamase inhibitor, is being developed by Wockhardt as a pharmacodynamically optimized fixed dose combination (FEP-2 g + TAZ-2 g) for the treatment of multidrug-resistant Gram-negative infections. To undertake an exposure-response analysis for establishing pharmacokinetic (PK)/pharmacodynamic (PD) targets, it is crucial to characterize the PK profile of compounds in surrogate compartments, such as plasma and lung, in clinically relevant animal infection models used to evaluate efficacy. In the current study, PKs of FEP and TAZ were assessed in plasma and in epithelial lining fluid (ELF) of neutropenic noninfected, lung-infected, and thigh-infected mice.
View Article and Find Full Text PDFVet World
July 2025
Division of Surgery, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Background And Aim: Antibiotic resistance poses a growing threat to wound management in veterinary medicine. Blue light phototherapy has emerged as a non-antibiotic bactericidal alternative with additional benefits for wound healing. However, its effectiveness in clinical veterinary contexts remains inadequately explored.
View Article and Find Full Text PDFMicrobiologyopen
October 2025
Department of Biochemistry, Faculty of Science and Technology, Chiromo Campus, Off Riverside Drive, University of Nairobi, Nairobi, Kenya.
Alkaline pectinases are in demand in industrial processes that require the degradation of plant pectins at high pH, for example, removal of pectin stains from fabrics, cutlery, and porcelain; treatment of pectic wastewater; fermentation of coffee, tea, and cocoa; manufacture of poultry and animal feeds, and processing of textiles, and so forth. The present study aimed to (a) screen four alkaliphilic microbial isolates, previously obtained from samples collected around Lake Bogoria (soda lake), Baringo County, Kenya, for alkaline pectinases, and (b) characterize the pectinase-producers. The screening data revealed that all the isolates were pectinase producers, exhibiting catalytic activities that ranged from 1.
View Article and Find Full Text PDFFood Res Int
November 2025
School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, PR China; Anqing Yixiu Green Food Innovation Research Institute, Anqing 246000, PR China. Electronic address:
This study presents a biopreservation method using sourdough co-fermented with Fructilactobacillus sanfranciscensis and Propionibacterium freudenreichii, optimizing conditions to 220 hydration and 24 h fermentation. The composite sourdough bread quality was evaluated through physicochemical, storage, sensory, and microbial tests, with mechanisms analyzed based on microstructure, rheology, and dough structure. Results showed that: first, the composite sourdough enhanced bread physicochemical properties, increasing volume, height-to-diameter ratio, elasticity, and resilience, while reducing baking loss, hardness, chewiness, and adhesiveness.
View Article and Find Full Text PDFBiol Rev Camb Philos Soc
September 2025
Department of Biological Sciences, University of Alberta, 116 ST and 83rd Ave, Edmonton, Alberta, T6G 2E9, Canada.
In social species, group functions often benefit from variation among individual group members. Many highly integrated social insect colonies rely on division of labour among colony members and emergent properties of their collective behaviour and physiology. Response threshold models are a prominent proximate explanation of division of labour, but how variation in response thresholds arise is largely unexplored.
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