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http://dx.doi.org/10.1001/jama.2025.2028 | DOI Listing |
J Med Virol
August 2025
Phase I Clinical Trial Research Ward, The Second Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Province, PR China.
Hepatitis B virus (HBV) infection remains a significant global public health challenge, contributing to both hepatic and extrahepatic disease burdens. This study aims to estimate the global disease and economic burden of HBV-attributable noncommunicable diseases (NCDs). The study included hepatic NCDs (cirrhosis and other chronic liver diseases [CCLDs] and hepatocellular carcinoma [HCC]) and nonhepatic NCDs (NHNCDs).
View Article and Find Full Text PDFTransplant Cell Ther
July 2025
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Department of Medicine, Weill Cornell Medical College, New York, New York.
Hematopoietic cell transplant (HCT) is a potentially curative treatment modality for patients with hematologic malignancies, but it can be associated with significant financial burden and toxicity due to increased medical expenditures (ie, prescription drugs). Prophylactic anti-infective medications are an essential component of allogeneic hematopoietic cell transplantation (allo-HCT) and help mitigate early post-transplant complications. Although these prophylactic anti-infective medications are essential, insurance barriers (ie, prior authorizations, denials, and high out-of-pocket costs) limit access for many patients and may result in reduced access to allo-HCT.
View Article and Find Full Text PDFAm Soc Clin Oncol Educ Book
June 2025
Instituto Nacional de Cancerología, Mexico City, Mexico.
Global cancer incidence is projected to rise dramatically, with over 35 million new cases anticipated by 2050, disproportionately affecting low- and middle-income countries (LMICs) where up to 70% of cancer deaths are expected to occur. This manuscript provides an in-depth assessment of the structural, economic, and sociocultural barriers that drive cancer care disparities in LMICs, including limited access to prevention, diagnosis, treatment, and palliative care services. Key challenges include shortages in oncology workforce, diagnostic infrastructure, radiotherapy access, and participation in clinical trials.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
July 2025
Department of Hospital Administration, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka India.
To project return on investments for a private ENT (Ear, nose & throat) autonomous surgical day care unit attached to large academic hospital, as a business model. Prospective, Observational study was conducted at two hospitals - a medical college hospital and a private hospital. Financial revenue generated from both hospitals was computed for a 1-year period.
View Article and Find Full Text PDFJ Int AIDS Soc
June 2025
Department of Work and Social Psychology, Maastricht University, Maastricht, The Netherlands.
Introduction: Several European countries show potential for pre-exposure prophylaxis (PrEP) provision expansion, with many men who have sex with men (MSM) on waiting lists. In the Netherlands, approximately 15,000 PrEP-eligible/intending MSM are awaiting PrEP access. We modelled the epidemiological and economic impact of extending PrEP provision considering several PrEP provision routes (National PrEP Programme and alternative PrEP providers).
View Article and Find Full Text PDF