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Article Abstract

Aims: To explore the potent anti-inflammatory and anti-tuberculosis potential of novel trimetallic Au-Pt-Cu nanofluids.

Materials & Methods: We employed BSA assay for anti-inflammatory assessment and tested anti-tuberculosis activity against H37Rv. Advanced molecular docking, dynamics, and DFT analyses were conducted to reveal interaction mechanisms and electronic properties.

Results: The nanofluids demonstrated impressive IC values (15.88 ± 0.09 μM and 0.54 ± 0.02 μg/ml), with strong binding affinities and stable interactions confirmed via molecular simulations. Favorable ADMET profiling highlights their promise as innovative therapeutic agents.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938965PMC
http://dx.doi.org/10.1080/17568919.2025.2478818DOI Listing

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