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http://dx.doi.org/10.1097/LVT.0000000000000607 | DOI Listing |
Hum Brain Mapp
September 2025
Tri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, and Emory University, Atlanta, Georgia, USA.
Investigating neuroimaging data to identify brain-based markers of mental illnesses has gained significant attention. Nevertheless, these endeavors encounter challenges arising from a reliance on symptoms and self-report assessments in making an initial diagnosis. The absence of biological data to delineate nosological categories hinders the provision of additional neurobiological insights into these disorders.
View Article and Find Full Text PDFNurs Inq
October 2025
Clinical Ethics and Spiritual Care Service, Provincial Health Services Authority, Vancouver, British Columbia, Canada.
Moral distress increased among healthcare workers during the first three years of the COVID-19 pandemic. This qualitative descriptive study explored the experiences of thirteen healthcare professionals with expertise in supporting healthcare workers experiencing moral distress within Canadian healthcare systems during this time. Participants reported multiple factors driving moral distress, such as resource scarcity (e.
View Article and Find Full Text PDFDiabet Med
September 2025
Endocrinology Department, East Surrey Hospital, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.
Aim: To explore the experiences of patients, families and clinicians managing steroid-induced hyperglycaemia (SIH) out of the hospital and identify areas for improved care.
Methods: We searched hospital records to identify patients requiring input from the diabetes inpatient team between February 2022 and March 2023 due to steroid usage. Clinicians, patients and their family members were interviewed remotely about their experiences of care and views on how to improve it.
Int Immunopharmacol
September 2025
Key Laboratory for Biorheological Science and Technology of Chinese Ministry of Education, National Local Joint Engineering Lab for Vascular Implants, College of Bioengineering, Chongqing University, Chongqing 400044, China; JinFeng Laboratory, Chongqing, 401329, China. Electronic address: wanggx@cq
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine that plays a crucial role in the pathophysiology of asthma, initiating multiple allergic cascade responses. Tezepelumab is the only monoclonal antibody currently approved for marketing, which acts by blocking TSLP binding to TSLPR. However, it is reported that a TSLP trap which simultaneously block TSLP binding with TSLPR and IL-7Rα has better efficiency in the repression of TSLP signal pathway.
View Article and Find Full Text PDFNurse Educ Pract
August 2025
University of Saskatchewan, 118 4400 - 4th Avenue, Regina, Saskatchewan S4T 0H8, Canada. Electronic address:
Aim: Vygotsky's social constructivist educational pedagogy as a way for registered nurses who teach to build psychologically safe and socially just learning environments for 'in practice' registered nurses with specific learning disorders.
Background: As a supportive educational brief, specific learning disorders, its occurrence in nursing, factors potentially having an impact on those with a specific learning disorder and what constitutes safe and just learning environments are outlined. Vygotsky's social constructivist educational pedagogy is an example of inclusive pedagogy whose integration can positively address specific learning needs.