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Pioneer is a single-crystal neutron diffractometer optimized for small-volume samples and weak signals at the Second Target Station at Oak Ridge National Laboratory. This paper presents the preliminary optical design progress, focusing on the rationale behind key design choices. It covers the T0 and bandwidth disk choppers, guide and beam control system, incident-beam polarizer, scattering beam collimators, and additional strategies. The chopper locations are selected to maximize neutron transport while taking advantage of standardized shielding structures. To accommodate the maintenance shield, operational shutter, and polarizing V-cavity, the guide design includes significant gaps. When these optical components are moved out of the beam path, oversized collimators, rather than guides, will be translated in. Pioneer will utilize slit packages to control beam size and divergence and a translatable polarizing V-cavity. Absorbing panels are strategically placed near the end station to minimize background. An oscillating radial collimator, operating in a shift mode, will be used with the vertical cylindrical detector, while a fixed multi-cone collimator will be used with the bottom flat detector. These collimators will enable the detection of weak signals when complex sample environments are used.
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http://dx.doi.org/10.1063/5.0247408 | DOI Listing |
Wounds
August 2025
Department of Nursing, Federal University of Ceará, Ceará, Brazil.
Background: Diabetic foot ulcers (DFUs) are a major clinical challenge, particularly among patients with refractory ulcers, that often lead to severe complications such as infection, amputation, and high mortality. Innovations supported by strong clinical evidence have the potential to improve healing outcomes, enhance quality of life, and reduce the economic burden on individuals and health care systems.
Objective: To describe the design of the concurrent optical and magnetic stimulation (COMS) therapy Investigational Device Exemption (IDE) study for refractory DFUs (MAVERICKS) trial.
Light Sci Appl
September 2025
National Laboratory of Solid State Microstructures, Key Laboratory of Intelligent Optical Sensing and Manipulation, College of Engineering and Applied Sciences, Nanjing University, 210023, Nanjing, China.
Planar optical elements incorporating space-varying Pancharatnam-Berry phase have revolutionized the manipulation of light fields by enabling continuous control over amplitude, phase, and polarization. While previous research focusing on linear functionalities using apolar liquid crystals (LCs) has attracted much attention, extending this concept to the nonlinear regime offers unprecedented opportunities for advanced optical processing. Here, we demonstrate the reconfigurable nonlinear Pancharatnam-Berry LC diffractive optics in photopatterned ion-doped ferroelectric nematics.
View Article and Find Full Text PDFLuminescence
September 2025
Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
A triphenyl-imidazole end-capped donor-acceptor type potential molecular probe 3 has been designed and synthesized. Probe 3 upon interaction with different classes of metal ions/anions and NPPs displayed high selectivity with CN anion (LOD = 20.42 nM) through fluorescence "turn-Off" response and a naked-eye sensitive visible color change.
View Article and Find Full Text PDFCont Lens Anterior Eye
September 2025
Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated People's Hospital of Northwest University, Xi'an 710004, China. Electronic address:
Background: Orthokeratology (OK) lenses have become a prevalent intervention for myopia control. However, lens decentration, a frequent complication, may influence the efficacy of myopia control. The aim of this study was to systematically assess the impact of OK lens decentration on axial length growth (ALG) in Chinese myopic children through a meta-analysis.
View Article and Find Full Text PDFJACC Cardiovasc Interv
September 2025
The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background: Previous trials have demonstrated increased 5-year risks for adverse clinical events after coronary artery implantation of poly-l-lactic acid-based bioresorbable scaffolds (BRS) compared with cobalt chromium (CoCr) everolimus-eluting stents (EES).
Objectives: The aim of this study was to evaluate the 5-year clinical outcomes of the novel sirolimus-eluting NeoVas BRS compared with CoCr EES.
Methods: A total of 560 patients with single de novo native coronary artery lesions with reference vessel diameter 2.