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In open-pit mining, autonomous trucks are essential for enhancing both safety and productivity. Object detection technology is critical to their smooth and secure operation, but training these models requires large amounts of high-quality annotated data representing various conditions. It is expensive and time-consuming to collect these data during open-pit mining due to the harsh environmental conditions. Simulation engines have emerged as an effective alternative, generating diverse labeled data to augment real-world datasets. However, discrepancies between simulated and real-world environments, often referred to as the Sim2Real domain shift, reduce model performance. This study addresses these challenges by presenting a novel semi-supervised domain adaptation for object detection (SSDA-OD) framework named Adamix, which is designed to reduce domain shift, enhance object detection, and minimize labeling costs. Adamix builds on a mean teacher architecture and introduces two key modules: progressive intermediate domain construction (PIDC) and warm-start adaptive pseudo-label (WSAPL). PIDC builds intermediate domains using a mixup strategy to reduce source domain bias and prevent overfitting, while WSAPL provides adaptive thresholds for pseudo-labeling, mitigating false and missed detections during training. When evaluated in a Sim2Real scenario, Adamix shows superior domain adaptation performance, achieving a higher mean average precision (mAP) compared with state-of-the-art methods, with 50% less labeled data required, achieved through active learning. The results demonstrate that Adamix significantly reduces dependence on costly real-world data collection, offering a more efficient solution for object detection in challenging open-pit mining environments.
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http://dx.doi.org/10.3390/s25051425 | DOI Listing |
J Nucl Med Technol
September 2025
Institute of Nuclear Medicine, First Faculty of Medicine, Charles University and the General University Hospital in Prague, Prague, Czech Republic;
The aim of the study was to validate a new method for semiautomatic subtraction of [Tc]Tc-sestamibi and [Tc]NaTcO SPECT 3-dimensional datasets using principal component analysis (PCA) against the results of parathyroid surgery and to compare its performance with an interactive method for visual comparison of images. We also sought to identify factors that affect the accuracy of lesion detection using the two methods. Scintigraphic data from [Tc]Tc-sestamibi and [Tc]NaTcO SPECT were analyzed using semiautomatic subtraction of the 2 registered datasets based on PCA applied to the region of interest including the thyroid and an interactive method for visual comparison of the 2 image datasets.
View Article and Find Full Text PDFExp Cell Res
September 2025
The Department of Hematology, The First Affiliated Hospital of Hainan Medical University, No.31 Longhua Road, Haikou City, Hainan Province, 570000, P.R. China. Electronic address:
Background: Nasopharyngeal carcinoma (NPC) is a kind of tumor disease with high malignant degree. CREPT expression was elevated abnormally in multi-cancers. However, the role and regulatory mechanism of CREPT in NPC remains unknown.
View Article and Find Full Text PDFBioinspir Biomim
September 2025
Mechanical Engineering, University of Massachusetts Dartmouth, 285 Old Westport Road, Dartmouth, Massachusetts, 02747-2300, UNITED STATES.
Harbor seals possess a remarkable ability to detect hydrodynamic footprints left by moving objects, even long after the objects have passed, through interactions between wake flows and their uniquely shaped whiskers. While the flow-induced vibration (FIV) of harbor seal whisker models has been extensively studied, their response to unsteady wakes generated by upstream moving bodies remains poorly understood. This study investigates the wake-induced vibration (WIV) of a flexibly mounted harbor seal-inspired whisker positioned downstream of a forced-oscillating circular cylinder, simulating the hydrodynamic footprint of a moving object.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
September 2025
Pharmacology and Toxicology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Gamal Abdel Nasser, 11835, New Cairo, Egypt.
Licochalcone A (LCA), a natural flavonoid with potent anti-inflammatory properties, has shown promise as a neuroprotective agent. However, its ability to cross the blood-brain barrier (BBB) and exert central effects remains underexplored. In this study, we demonstrate for the first time that LCA enhances cognitive function in a lipopolysaccharide (LPS)-induced neuroinflammatory mouse model and effectively penetrates the BBB.
View Article and Find Full Text PDFAquac Nutr
August 2025
Guangdong Provincial Key Laboratory of Aquatic Animal Disease Control and Healthy Culture and Key Laboratory of Control for Disease of Aquatic Animals of Guangdong Higher Education Institutes, Fisheries College, Guangdong Ocean University, Zhanjiang, China.
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an essential component in regulating oxidative stress. Sulforaphane (SFN) is a natural antioxidant and gene agonist that can increase the antioxidant capacity of the organism and reduce oxidative stress. However, research on the repair of oxidative stress damage by SFN in aquatic animals remains extremely scarce.
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