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Inertial navigation systems (INSs) provide autonomous position estimation capabilities independent of global navigation satellite systems (GNSSs). However, the high cost of traditional sensors, such as fiber-optic gyroscopes (FOGs), limits their widespread adoption. In contrast, micro-electromechanical system (MEMS)-based inertial measurement units (IMUs) offer a low-cost alternative; however, their lower accuracy and sensor bias issues, particularly in maritime environments, remain considerable obstacles. This study proposes an improved method for bias estimation by comparing the estimated values from a trajectory generator (TG)-based acceleration and angular-velocity estimation system with actual measurements. Additionally, for - and -axis accelerations, we introduce a method that leverages the correlation between altitude differences derived from an INS/GNSS/gyrocompass (IGG) and those obtained during the TG estimation process to estimate the bias. Simulation datasets from experimental voyages validate the proposed method by evaluating the mean, median, normalized cross-correlation, least squares, and fast Fourier transform (FFT). The Butterworth filter achieved the smallest angular-velocity bias estimation error. For - and -axis acceleration bias, altitude-based estimation achieved differences of 1.2 × 10 m/s and 1.0 × 10 m/s, respectively, by comparing the input bias using 30 min data. These methods enhance the positioning and attitude estimation accuracy of low-cost IMUs, providing a cost-effective maritime navigation solution.
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http://dx.doi.org/10.3390/s25051315 | DOI Listing |
JAMA Netw Open
September 2025
Division of Gastroenterology, Department of Medicine, University of California San Diego, La Jolla.
Importance: Janus kinase (JAK) inhibitors are highly effective medications for several immune-mediated inflammatory diseases (IMIDs). However, safety concerns have led to regulatory restrictions.
Objective: To compare the risk of adverse events with JAK inhibitors vs tumor necrosis factor (TNF) antagonists in patients with IMIDs in head-to-head comparative effectiveness studies.
J Acoust Soc Am
September 2025
ENTPE, Ecole Centrale de Lyon, CNRS, LTDS, UMR5513, 69518 Vaulx-en-Velin, France.
This study investigated the potential role of temporal, spectral, and binaural room-induced cues for the perception of virtual auditory distance. Listeners judged the perceived distance of a frontal source simulated between 0.5 and 10 m in a room via headphones, with eyes closed in a soundproof booth.
View Article and Find Full Text PDFJ Robot Surg
September 2025
Department of Urology/School of Clinical Medicine, North Sichuan Medical College/Affiliated Hospital of North Sichuan Medical College, No. 1, South Maoyuan Road, Shunqing District, Nanchong City, 63700, Sichuan Province, China.
Renal transplantation is the best option for end-stage renal disease, and in this study, patients who underwent robotic-assisted renal transplantation (RAKT) and open renal transplantation (OKT) were selected to compare their intraoperative and postoperative clinical outcomes: including Operation Time, Length of Stay, WIT (warm ischaemia time), CIT (cold ischaemia time), Estimated Blood Loss, Post 1 month Creatinine, Incision Length, Rewarming Time, Wound infection. The study was registered in PROSPERO with CRD code: CRD420251061084. We searched in Web of Science, Pubmed, Wiely, Elsevier databases, screened according to inclusion and exclusion criteria and finally included 7 papers.
View Article and Find Full Text PDFJ Comp Eff Res
September 2025
British Heart Foundation, University of Glasgow, Glasgow, UK.
Composite endpoints amalgamate multiple clinical outcomes into a single measure, offering efficiency gains in clinical trials through increased event rates and reduced sample sizes, thus accelerating clinical development and regulatory approval. However, employing composite endpoints introduces complexities into health technology assessments (HTAs), particularly in economic modeling, due to the varying clinical significance and cost implications of the components. In this paper, we explore best modeling practice for HTAs that are based on clinical trials that employ composite endpoints.
View Article and Find Full Text PDF