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BackgroundOrthogonal translation computed laminography (OTCL) has great potential for tiny fault detection in laminated structure thin-plate parts. It offers a larger magnification ratio but generates limited projection data, which would result in aliasing artifacts in the reconstructed image.ObjectiveOne way to minimize these artifacts is to use prior information, such as the piecewise constant property and prior image information. This work was inspired by the adaptive-weighted high order total variation (awHOTV) model, which is known for its ability to protect edge and detail information. Meanwhile, the laminated structure thin-plate parts are printed using computer-aided design (CAD) images, which provide structural information.MethodsTo create a reliable CAD information beforehand, we adopted a two-in-one estimation method. Therefore, combining the CAD information with the awHOTV model, we propose an improved adaptive weighted higher-order TV (Cpi-awHOTV) model based on the CAD prior and use the adaptive steepest descent projection onto convex set (ASD-POCS) algorithm to solve the imaging model.ResultsTo evaluate the performance of our algorithm, we compared it with existing filtered back projection (FBP), simultaneous algebraic reconstruction technique (SART), total variation (TV), adaptive-weighted TV (awTV), and high order TV (HOTV)algorithms on phantom1 and phantom2 with various scanning angle ranges. Additionally, we used the phantom2 as the CAD prior in real data experiments. The results show that, the Cpi-awHOTV algorithm can obtain high-quality reconstructed images and better quantitative evaluation indicators.ConclusionsVisual inspection and quantitative analysis of reconstructed images demonstrate that the Cpi-awHOTV algorithm effectively protects edge information, and reduces aliasing artifacts due to interference from adjacent slice structures.
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http://dx.doi.org/10.1177/08953996241299988 | DOI Listing |
Acad Radiol
September 2025
Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan (J.Y.H., C.L.K., K.L.C.); College of Medicine, National Taiwan University, Taipei, Taiwan (J.Y.H., C.K.H., K.L.C., Y.W.W.); Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan (C.K
Rationale And Objectives: The prognostic implications of myocardial perfusion imaging (MPI) are imperative to provide proper management of coronary artery disease (CAD). This study aimed to quantify the long-term prognostic value of MPI under routine clinical conditions.
Materials And Methods: This single-center retrospective cohort study evaluated all-cause mortality and cause-specific survival according to MPI findings in patients with suspected or known CAD who underwent diagnostic evaluation or assessment of myocardial ischemia and viability in a tertiary referral cardiovascular center.
Clin Neurol Neurosurg
September 2025
Department of Neurology, UPMC, Pittsburgh, PA, USA. Electronic address:
Background: Final infarct volume (FIV) is a strong predictor of stroke outcomes. Although smaller FIV are associated with better outcomes, many patients fail to achieve functional independence. We aimed to identify poor outcome predictors in patients with anterior large vessel occlusion stroke (LVOS) who underwent mechanical thrombectomy (MT) and had small FIV.
View Article and Find Full Text PDFBMJ Open
September 2025
Centro de Investigaciones Clínicas, Fundación Valle del Lili Cali, Cali, Valle del Cauca, Colombia
Introduction: Elevated lipid profiles increase the risk of atherosclerotic cardiovascular disease (ASCVD), a leading cause of mortality worldwide. Despite the availability of lipid-lowering therapy (LLT), adherence to therapy and achievement of Low-Density Lipoprotein Cholesterol (LDL-C) target levels remain suboptimal. Coronary artery disease (CAD) presents substantial public health challenges, with LDL-C goal attainment rates reported to be between 30.
View Article and Find Full Text PDFVasa
September 2025
Southwest Medical University, Luzhou, Sichuan province, China.
Peripheral arterial disease (PAD) is associated with an increased risk of major adverse cardiovascular and limb events. However, the factors influencing major adverse cardiovascular events (MACE) and major adverse limb events (MALE) in patients with PAD remain unclear. Additionally, while some predictive models for MACE and MALE in patients with PAD have been developed, their performance is uncertain.
View Article and Find Full Text PDFSci Rep
September 2025
Laboratory of Frigid Zone Cardiovascular Disease, Cardiovascular Research Institute, Department of Cardiology, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenhe Distract, Shenyang, 110016, China.
To assess the value of computed tomography angiography (CTA)-derived fractional flow reserve (CT-FFR) and high-risk plaque characteristics (HRPC) in the prediction of prognosis in patients with concomitant aortic stenosis (AS) and coronary artery disease (CAD) after transcatheter aortic valve replacement (TAVR). The study was a post hoc analysis from a multicenter TAVR registry. Patients with AS and obstructive CAD who underwent successful TAVR treatment were enrolled.
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