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Background: Asthma education programs (AEPs) are crucial to improving patient outcomes, but few patients participate. Therefore, an online asthma education program (electronic AEP, eAEP) has been developed. We aimed to investigate the effectiveness of the eAEP in adults with asthma in terms of asthma knowledge, symptom control and emergency treatments.
Methods: In a cluster randomised controlled trial, general practitioner (GP) practices were randomly assigned to either access to the intervention (eAEP), or usual care (UC) control. Outcomes were assessed at baseline, two weeks, three and six months. Primary endpoint was the difference in Asthma Knowledge Test (AKT) scores after completion of the eAEP/UC. Secondary outcomes included symptom control (Asthma Control Test, ACT) and emergency treatments.
Findings: 62 patients from 10 intervention practices and 46 patients from 11 control practices were analysed. The intervention group had significantly greater improvements in mean AKT scores (between-group adjusted mean difference (AMD), 9.3 (95 % CI 6.3-12.3), p < 0.001) at the primary endpoint. Differences remained relatively stable during the six-month follow-up. Between-group AMD in the ACT was 1.4 (95 % CI -0.1-2.8, p < 0.062) three months after the eAEP/UC and 1.6 (95 % CI 0.2-2.9, p < 0.023) at study end. More intervention group patients demonstrated the inhalation technique correctly (98 % vs. 79 %, p = 0.007), received peak expiratory flow instructions (94 % vs. 32 %, p < 0.001) and an asthma action plan (96 % vs. 50 %, p < 0.001).
Interpretation: The eAEP was effective in improving knowledge over six months and showed beneficial effects on symptom control. The eAEP may contribute to improved asthma care in GP settings.
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http://dx.doi.org/10.1016/j.rmed.2025.108041 | DOI Listing |
J Phys Act Health
September 2025
Department of Neurology, Langfang People's Hospital, Langfang, HE, China.
Background: As China's population ages, chronic noncommunicable diseases have become increasingly prevalent. While physical activity (PA) is known to reduce disease risk, the role of intensity-light, moderate, or vigorous-remains unclear.
Methods: Using 5 waves (2011-2020) of China Health and Retirement Longitudinal Study data (N = 54,300), this study examined associations between PA intensity and the prevalence of 13 chronic diseases.
Ann Allergy Asthma Immunol
September 2025
University of Illinois Chicago, Department of Medicine and Department of Pediatrics. Electronic address:
Ann Allergy Asthma Immunol
September 2025
Department of Pneumology, University Hospital Saint-Luc, Brussels, Belgium; Pole Pneumology, ENT, and Dermatology - LUNS, Institute of Experimental and Clinical Research (IREC), UCLouvain, Brussels, Belgium.
Background: Different biologics available as add-on treatment for severe asthma (SA) showed modest benefits on lung function parameters but head-to-head comparisons are lacking.
Objective: This study aims to compare the effects of four biologics on lung function parameters (including small airways) at 6 and 12 months of treatment in patients with SA.
Methods: An observational multicenter study was conducted on adults patients with SA naïve to biologics treated by benralizumab, dupilumab, mepolizumab and omalizumab with lung function assessment by spirometry and gas dilution method at baseline (T0), after 6 (T6) and 12 months (T12) of treatment.
Ann Allergy Asthma Immunol
September 2025
Department of Pediatrics, Hassenfeld Children's Hospital, NYU Grossman School of Medicine, New York, New York; Department of Pediatrics, Gastroenterology and Nutrition, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
There has been substantial growth of Advanced Practice Practitioners (APPs) in health care since their inception in the 1960's with APPs providing high quality and cost-effective care in a variety of medical settings. While most of the growth is in primary care, APPs are becoming increasingly leveraged in subspeciality care including Allergy & Immunology (A&I). At present there is limited literature on APPs in A&I specifically but there is growing literature on APP utilization and training in other specialties.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
Postgraduate training base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, China.
Asthma is a chronic inflammatory respiratory disease influenced by genetic and environmental factors. Emerging evidence suggests that microplastics and nanoplastics (NPs) pose significant health risks. When inhaled, these tiny particles can accumulate in the lungs, triggering inflammation, oxidative stress, and other disruptions in pulmonary function.
View Article and Find Full Text PDF