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BACKGROUND : Colorectal polypectomy is operator dependent, with variable rates of complete resection. The currently available assessment tools do not provide specific competency-based evaluation of provider technique. We aimed to validate the Global Polypectomy Assessment Tool (GPAT), a novel competency assessment tool for colorectal polypectomy. METHODS : GPAT was derived from the ESGE Curriculum for Training in endoscopic mucosal resection in the colon. Members of the curriculum taskforce plus three invited trainees and three medical students (collectively: the assessors) anonymously assessed nine endoscopic-view only polypectomy videos. The primary end point was the correlation of the assessors' GPAT scores with a consensus-derived reference GPAT score per video. Secondary end points were the assessors' subjective impression versus their GPAT score and interobserver agreement among assessors' GPAT scores. RESULTS : 171 GPAT assessments by 19 assessors (consultant gastroenterologists [n = 10], trainee gastroenterologists [n = 4], consultant surgeons [n = 2], and medical students [n = 3]) were analyzed. Reference GPAT scores did not differ significantly from those of the assessors (73.1 % [95 %CI 64.6 %-81.6 %] vs. 69.3 % [95 %CI 64.9 %-81.2 %]; = 0.47). There was moderate IOA in GPAT scores among gastroenterologists (intraclass correlation coefficient [ICC], 0.52 [moderate]) but not among nongastroenterologists (ICC 0.32 [poor]). GPAT correlated with assessors' subjective impression of polypectomy quality (correlation coefficient 0.98 [95 %CI 0.90-1.00]; < 0.001). Overall assessors' qualitative usability scoring of GPAT was positive. CONCLUSIONS : GPAT allows standardized scoring of polypectomies, with moderate IOA among gastroenterologists and correlation with subjective impressions of polypectomy quality. GPAT could standardize assessment of trainee polypectomy competency offering structured feedback on performance.
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http://dx.doi.org/10.1055/a-2541-4028 | DOI Listing |
Laryngoscope
July 2025
Department of Otolaryngology-Head & Neck Surgery, University of Missouri, Columbia, South Carolina, USA.
Objectives: To analyze the synergistic effects of myofascial release physical therapy (MFRPT) and voice therapy (VT) in reducing symptom severity for patients diagnosed with cervicalgia and associated functional laryngeal conditions.
Methods: This retrospective analysis included adult patients with cervicalgia and functional laryngeal conditions-muscle tension dysphonia (MTDa), muscle tension dysphagia (MTDg), chronic cough (CC), or globus sensation (GP)-at a tertiary care center. Patients received MFRPT, VT, or a combination of both (VT + MFRPT).
Endoscopy
May 2025
Department of Gastroenterology, Faculty of Medicine and Health Sciences, University of Ghent, Ghent, Belgium.
BACKGROUND : Colorectal polypectomy is operator dependent, with variable rates of complete resection. The currently available assessment tools do not provide specific competency-based evaluation of provider technique. We aimed to validate the Global Polypectomy Assessment Tool (GPAT), a novel competency assessment tool for colorectal polypectomy.
View Article and Find Full Text PDFFront Immunol
March 2023
Organ Transplantation Clinical Medical Center of Xiamen University, Department of Organ Transplantation, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Background: Liver cancer is the sixth most commonly diagnosed cancer and the third leading cause of cancer-related death worldwide. Hepatocellular carcinoma accounts for an estimated 90% of all liver cancers. Many enzymes of the GPAT/AGPAT family are required for the synthesis of triacylglycerol.
View Article and Find Full Text PDFAutophagy
January 2022
Department of Cell Biology, University of Groningen, University Medical Center Groningen, AV Groningen, The Netherlands.
Autophagic pathways cross with lipid homeostasis and thus provide energy and essential building blocks that are indispensable for liver functions. Energy deficiencies are compensated by breaking down lipid droplets (LDs), intracellular organelles that store neutral lipids, in part by a selective type of autophagy, referred to as lipophagy. The process of lipophagy does not appear to be properly regulated in fatty liver diseases (FLDs), an important risk factor for the development of hepatocellular carcinomas (HCC).
View Article and Find Full Text PDFBMC Public Health
January 2018
Department of Health Sciences, VU University of Amsterdam, De Boelelaan 1085, 1081HV, Amsterdam, The Netherlands.
Background: Evaluation and monitoring methods are often unable to identify crucial elements of success or failure of integrated community-wide approaches aiming to tackle childhood overweight and obesity, yet difficult to determine in complex programmes. Therefore, we aimed to systematically appraise strengths and weaknesses of such programmes and to assess the usefulness of the appraisal tools used.
Methods: To identify strengths and weaknesses of the integrated community-based approaches two tools were used: the Good Practice Appraisal tool for obesity prevention programmes, projects, initiatives and intervention (GPAT), a self-administered questionnaire developed by the WHO; and the OPEN tool, a structured list of questions based on the EPODE theory, to assist face-to-face interviews with the principle programme coordinators.