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Unlabelled: Cavernous hemangiomas are venous malformations characterized by interconnected channels of abnormally dilated blood vessels having low flow of blood. Whilst venous malformations most commonly affect the head and neck region, isolated cavernous hemangiomas of the palatine tonsils are extremely rare; with only 4 cases being reported in the English Literature. We report a case of a 43-year-old female who was referred to us for the evaluation and management of a right tonsillar swelling. Clinico-radiological findings were highly suggestive of a tonsillar hemangioma. Surgical excision of the right palatine tonsil along with the lesion was performed after which there was complete resolution of symptoms. Histopathological analysis confirmed a diagnosis of a tonsillar cavernous hemangioma.
Supplementary Information: The online version contains supplementary material available at 10.1007/s12070-024-05153-1.
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http://dx.doi.org/10.1007/s12070-024-05153-1 | DOI Listing |
Fukushima J Med Sci
September 2025
Department of Otolaryngology-Head and Neck Surgery, Kanazawa University.
Purpose: Recurrent respiratory papillomatosis (RRP) is associated with low-risk types of human papillomavirus (HPV). With HPV DNA testing, the oral rinse of RRP patients may be a useful liquid biopsy, as previously shown in patients with oropharyngeal cancer.
Methods: Oral rinse, along with palatine and pharyngeal tonsil swabs, were collected from seven patients with persistent RRP.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
September 2025
Day surgery is an important part of the comprehensive reform of public hospitals, which is conducive to improving hospital management level, enhancing medical service efficiency, and controlling medical expenses. The National Health Commission has included tonsillectomy and/or adenoidectomy in the recommended list of daytime surgeries. However, there is no unified understanding and clinical practice of tonsillar and/or adenoid day surgery in China.
View Article and Find Full Text PDFRen Fail
December 2025
Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University, Asahikawa, Japan.
An aberrant mucosal immune response against commensal bacteria in the tonsils is hypothesized to be one of the pathogenic mechanisms underlying immunoglobulin A nephropathy (IgAN). However, the bacteria involved in the pathogenesis of IgAN have not been fully elucidated. In this study, we compared the differences in tonsillar bacterial flora between IgAN ( = 101) and recurrent tonsillitis (RT) ( = 117) based on swab cultures from tonsillar surfaces and the center of the tonsils.
View Article and Find Full Text PDFBMC Cancer
September 2025
Institute of Virology, National Reference Center for Papilloma - and Polyomaviruses, University of Cologne, Faculty of Medicine and University Hospital Cologne, Fuerst-Pueckler-Str. 56, Cologne, 50935, Germany.
Background: Human papillomavirus (HPV)-associated oropharyngeal cancer (OPC) is increasing, with HPV16 being the most prevalent type. Persistent oral HPV infections play a causal role in the pathogenesis of these cancers. The objective of this systematic review was to summarize current data on oral HPV prevalence in the general population and in people living with HIV (PLWH), possible effects of prophylactic vaccination and optimal sampling methods for the detection of HPV in the oral cavity.
View Article and Find Full Text PDFPLoS Pathog
August 2025
Translational Gastroenterology and Liver Unit, University of Oxford, Oxford, United Kingdom.
The COVID-19 pandemic response demonstrated the effectiveness of adenovirus vector vaccines in inducing protective cellular and antibody responses. However, we still lack mechanistic understanding of the factors regulating immunity induced by this platform, especially innate pathways. We utilized a human tonsil organoid model to study the regulation of adaptive responses to ChAdOx1 nCoV-19.
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