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Aim: This study aims to analyze the fatigue resistance, surface mechanical properties, and biomechanical responsiveness of microtissue-engineered root dentin using cellulose nanofibers, hydroxyapatite nanocrystals, and walnut shell nanopowders.
Methodology: The objectives are to evaluate the differences in fatigue resistance and biomechanics and surface mechanical characteristics by infiltrating these nanomaterials into the root canal of endodontically treated teeth. Forty human permanent single-rooted teeth were collected with the patient's consent. Fatigue resistance was measured using cyclic loading, and surface roughness was measured by scanning electron microscopy (SEM).
Results: The results showed a fatigue resistance of 36.81 ± 4.58 MPa, attributed to the availability of calcium ions at 9%, the highest compared to other groups. Non-microtissue-engineered root dentin exhibited a stress resistance of 12.3 ± 3.1 MPa and a strain resistance of 4.1 ± 1.1 MPa. Walnut shell nanopowder (WNP) exhibited higher fatigue resistance than other groups ( > 0.05).
Conclusion: Root dentin engineered with HaNPs showed a fatigue resistance of 36.81 ± 4.58 MPa and surface roughness of 4.2 ± 0.5 MPa, attributed to the availability of calcium ions at 9%, the highest compared to other groups. Non-microtissue-engineered root dentin exhibited a fatigue resistance of 12.3 ± 3.1 MPa, while microtissue-engineered root dentin showed 36.81 ± 4.58 MPa, which is three times higher.
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http://dx.doi.org/10.4103/jpbs.jpbs_1196_24 | DOI Listing |
Sci Adv
September 2025
State Key Laboratory of Bioinspired Interfacial Materials Science, School of Nano Science and Technology, Suzhou Institute for Advanced Research, University of Science and Technology of China, Suzhou 215123, P. R. China.
Acoustic transducers require films that demonstrate both toughness and fatigue resistance, presenting notable challenges when achieved through conventional nanoscale reinforcing strategies. Here, we found that the rib structure of a cicada's tymbal exhibits exceptional toughness and fatigue resistance, attributed to its unique architecture composed of alternating soft and stiff polymer layers. Inspired by this rib structure, we developed a robust artificial rib film (ARF) using a nanoconfined crystallization strategy that involves the deposition of soft polyethylene oxide and stiff phenol formaldehyde.
View Article and Find Full Text PDFInfect Dis Ther
September 2025
Department of Nursing, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, China.
Introduction: Cognitive frailty (CF), which typically precedes dementia and functional decline, serves as a more robust predictor of adverse health outcomes compared to physical frailty alone, representing a critical challenge in promoting healthy aging among older people living with HIV (PLWH) aged ≥ 50 years. This study aimed to investigate the prevalence of cognitive frailty and identify its associated factors among PLWH aged ≥ 50 years.
Methods: A convenience sample of 344 PLWH ≥ 50 years was recruited from a tertiary Grade A hospital in Zunyi, China.
Small
September 2025
Smart Material Research Laboratory, Department of Physics, Indian Institute of Technology Roorkee, Roorkee, 247667, India.
Achieving superior energy storage performance in dielectric materials under low electric fields remains a challenge. Most recent advancements require high fields that limit device applicability. Developing dielectric capacitors with high recoverable energy density (W), efficiency (η), and energy-storage coefficient (W/E) at low/moderate fields is critical for safer, compact, and durable electronics.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Social Science, Malawi Liverpool Wellcome Clinical Programme, Blantyre, Malawi.
Diarrhoea due to rotavirus remains a significant cause of child mortality in developing regions. Caregivers' perspectives on the social determinants of gastroenteritis and childhood vaccination, including the rotavirus vaccine, were explored through focus group discussions in Ethiopia (n = 6), Kenya (n = 14), and Malawi (n = 10), using a combination of thematic and framework analysis approaches. The results show that diarrhoea was perceived to be a burden in all three countries, particularly among infants, due to challenges in WASH (water, sanitation, and hygiene) infrastructures and poverty.
View Article and Find Full Text PDFInt J Sports Physiol Perform
September 2025
Discipline of Exercise and Sport Science, School of Health Sciences, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.
Purpose: This study examined the effects of cluster sets (CS) versus traditional sets (TRAD) on performance and perceptual responses during pneumatic chest press (CP) and leg press (LP). Exercise-specific differences and the influence of sex and strength were also explored.
Methods: Forty-seven recreationally resistance-trained young adults (23 male and 24 female) performed CP and LP at 70% 1-repetition maximum in either CS (4 × [2 × 5], 30-s intraset rest, 150 s between sets) or TRAD (4 × 10, 180-s rest between sets) in randomized order.