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Revisiting hypertension prevalence and risk factors: prevalence of hypertension and risk of diabetes in China.
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Department of Cardiology, First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, Heilongjiang, 150001, China.
Background: Hypertension is a common and serious public health issue, with elevated blood pressure significantly increasing the risk of cardiovascular disease and diabetes. In adults, blood pressure values of 130–139 mm Hg/80–89 mm Hg are associated with an increasing relative risk of cardiovascular complications and mortality. According to the American College of Cardiology (ACC) / American Heart Association (AHA) criteria for the diagnosis of hypertension, this study aimed to describe the prevalence and risk factors for stage 1 (systolic blood pressure 130–139 mm Hg or diastolic blood pressure 80–89 mm Hg) and stage 2 (systolic blood pressure ≥ 140 mm Hg or diastolic blood pressure ≥ 90 mm Hg) hypertension.
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View Article and Find Full Text PDFStatins are the most commonly used cholesterol-lowering medications, with proven efficacy in reducing cardiovascular disease in humans; however, statins are associated with a higher risk of new-onset type 2 diabetes (T2D). Mechanisms contributing to statin-induced diabetes are not well understood and may include effects on body composition, tissue insulin sensitivity, and/or pancreatic β-cell function. Given the essential role of the β-cell in maintaining normoglycemia, this review focuses on how statins may lead to the demise of the β-cell.
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Liggins Institute, Waipapa Taumata Rau The University of Auckland, Auckland 1142, New Zealand.
The non-communicable disease (NCD) burden in the Cook Islands is severe; 62% of adults 18-69 years live with 3-5 risk factors. Understanding NCD complexity and developing evidence-based actions to mitigate this burden is crucial. This article reports on the evolution of a sustained health promotion programme contributing to understanding adolescent metabolic health in Rarotonga.
View Article and Find Full Text PDFProcessing UK Biobank High Resolution Accelerometry Data for Unsupervised Identification of Activity Profiles and Their Differences in Clinically Relevant Outcome Parameters - The ATLAS Index Revisited.
Stud Health Technol Inform
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Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School, Germany.
Accelerometer data obtained with wearable devices over extended periods of time provides objective, valuable information on activity behavior. Building on previous work to derive easy-to-interpret activity parameters - the Activity Types from Long-term Accelerometric Sensor data (ATLAS) index - from such data, we aim to investigate whether this approach is feasible with high-quality, extensive data from the UK Biobank, for identifying activity behavior groups, and if exemplary, clinically relevant parameters differ between these groups. A sample of 6,400 subjects' raw accelerometer data was chosen to be processed for computation of the ATLAS index parameters 'regularity', 'intensity' and 'duration' of moderate-intensity, 15+-minute physical activity events.
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