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High-temperature thin-film sensors (HTTSs) offer promising solutions for in situ monitoring of various thermal and mechanical parameters in extreme environments. However, maintaining their stable operation at high temperatures exceeding 1000 °C for extended durations remains challenging due to severe material degradation. This study first demonstrates a microstructural engineering strategy to enhance the thermal endurance of metal oxide thin films through integrating high-melting-point metal oxide nanophases. Using standard Micro-Electro-Mechanical System (MEMS) technologies, alumina (AlO) is atomically integrated into indium tin oxide (ITO) thin films. The influence of AlO doping on the ITO matrix under various high-temperature conditions, with emphasis on the variations of chemical composition, crystal structure, morphology, recrystallization, and sensing behavior, is systematically investigated. An optimized film, characterized by an Al/In ratio of 1.57 wt.%, exhibits a record-low resistance drift of 0.002% h during a 10 h exposure at 1200 °C.
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http://dx.doi.org/10.1002/smll.202500339 | DOI Listing |
Nat Nanotechnol
September 2025
School of Engineering, The University of Tokyo, Tokyo, Japan.
Active metasurfaces incorporating electro-optic materials enable high-speed free-space optical modulators that show great promise for a wide range of applications, including optical communication, sensing and computing. However, the limited light-matter interaction lengths in metasurfaces typically require high driving voltages exceeding tens of volts to achieve satisfactory modulation. Here we present low-voltage, high-speed free-space optical modulators based on silicon-organic-hybrid metasurfaces with dimerized-grating-based nanostructures.
View Article and Find Full Text PDFLight Sci Appl
September 2025
Department of Electrical, Electronic, and Communication Engineering, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, 112-8551, Japan.
While non-destructive in-line monitoring at manufacturing sites is essential for safe distribution cycles of pharmaceuticals, efforts are still insufficient to develop analytical systems for detailed dynamic visualisation of foreign substances and material composition in target pills. Although spectroscopies, expected towards pharma testing, have faced technical challenges in in-line setups for bulky equipment housing, this work demonstrates compact dynamic photo-monitoring systems by selectively extracting informative irradiation-wavelengths from comprehensive optical references of target pills. This work develops a non-destructive in-line dynamic inspection system for pharma agent pills with carbon nanotube (CNT) photo-thermoelectric imagers and the associated ultrabroadband sub-terahertz (THz)-infrared (IR) multi-wavelength monitoring.
View Article and Find Full Text PDFBioresour Technol
September 2025
School of Environment, Northeast Normal University, Changchun 130117, PR China.
Heavy metals such as Cu are widely prevalent in wastewater (typically 0.04-157.4 mM in typical treatment systems), threatening microbial communities critical for pollutant removal.
View Article and Find Full Text PDFBiochem Biophys Res Commun
August 2025
Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA, 02139, USA. Electronic address:
Superparamagnetic iron oxide nanoparticles (SPIONs) have emerged as powerful tools in nanomedicine owing to their heavy-metal-free composition, distinct magnetic properties, biocompatibility, and customizable surface chemistry. While traditionally employed as T-weighted MRI contrast agents, recent innovations have enabled the development of ultra-small SPIONs-such as exceedingly small SPIONs (ES-SPIONs) and single-nanometer iron oxide nanoparticles (SNIOs)-that offer T-weighted MRI capabilities, which are favored by radiologists for their superior anatomical clarity. This review highlights the synthesis of monodisperse SPIONs via thermal decomposition and controlled oxidation, as well as their functionalization with zwitterionic dopamine sulfonate (ZDS) ligands, which confer colloidal stability, minimal protein adsorption, and efficient renal clearance.
View Article and Find Full Text PDFJ Trace Elem Med Biol
September 2025
Department of Neurology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China. Electronic address:
Objective: We previously documented that exposure to a spectrum of elements is associated with autism spectrum disorder (ASD). However, there is a lack of mechanistic understanding as to how elemental mixtures contribute to the ASD development.
Materials And Methods: Serum and urinary concentrations of 26 elements and six biomarkers of ASD-relevant pathophysiologic pathways including serum HIPK 2, serum p53 protein, urine malondialdehyde (MDA), urine 8-OHdG, serum melatonin, and urine carnitine, were measured in 21 ASD cases and 21 age-matched healthy controls of children aged 6-12 years.