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http://dx.doi.org/10.1183/23120541.00713-2024 | DOI Listing |
Eur J Neurol
September 2025
Pain Treatment and Evaluation Center, CHU Timone, Assistance Publique des Hôpitaux de Marseille, Marseille, France.
Background: Neuropathic pain (NP) is frequently resistant to conventional treatments. Botulinum toxin type A (BT-A) is a recommended option for focal peripheral NP, but the dynamics of its effect in real-life conditions remain poorly characterized.
Objective: To assess BT-A efficacy in a real-world study of patients with focal peripheral NP, over a 1-year follow-up period.
Contemp Clin Trials
September 2025
Quantitative Sciences Unit, Stanford School of Medicine, United States of America.
Background: Non-collegiate young adults engage in high rates of heavy drinking but are less likely to access alcohol-related counseling or treatment. Peers play a significant role in shaping drinking behavior, yet few interventions target close peer influence in this population.
Methods: This two-arm randomized controlled trial will enroll 300 young adults aged 18-25 who report 2+ heavy drinking days (HDD; defined as 4+ drinks for a woman and 5+ drinks for a man) in the past 30 days and are not enrolled in college.
Cien Saude Colet
August 2025
School of Public Health, Harvard University. Boston Estados Unidos.
In this multicenter, cross-sectional and quantitative study we evaluated the influence of urban violence and COVID-19 on the work process and team rapport of community health workers (CHWs) in eight municipalities of Northeastern Brazil. The collected information covered sociodemographics, work routines, exposure to violence, self-efficacy and coronavirus anxiety. A logistic regression was performed using as outcome variable the answer to the question: "Do you think your team work process changed during the pandemic?" The sample included 1,944 CHWs, of whom 56.
View Article and Find Full Text PDFSleep
September 2025
Center for Sleep Medicine, Hospices Civils de Lyon, Lyon 1 University, Lyon, F-69000, France.
Current treatments for narcolepsy type 1 (NT1) have little impact on psychiatric, cognitive and metabolic comorbidities. Here, we evaluated the feasibility, safety and efficacy of a prospective Exercise Training (ET) program on sleep-related symptoms and comorbidities in NT1. Sedentary adult with NT1 participated in a 6-week supervised ET program followed by a 18-week self-directed program.
View Article and Find Full Text PDFClimacteric
September 2025
Palacios Institute of Women's Health, Madrid, Spain.
For women with mild-to-moderate menopausal symptoms, lifestyle changes and over-the-counter products and services can be beneficial for symptom management, especially for those who are contraindicated or averse to using menopausal hormone therapy (MHT). Lifestyle changes, such as increased exercise and improvements in diet, enhance overall health and are suggested by some low-level evidence - largely from observational studies - to alleviate menopausal symptoms. Over-the-counter dietary and herbal supplements are a popular alternative to MHT.
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