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Recently, pixel-to-pixel contrastive learning in single-scale feature space has been widely studied in semantic segmentation to learn a unified feature expression for pixels of the same category. However, the unified representation is too extreme, and the receptive field of each single-scale pixel is limited, which is insufficient to reflect the representative features of the category. To address these problems, this article extends the single-scale feature space to that of multiscale and proposes a hierarchical contrastive learning (Hi-CL) method to explore pixel-to-component semantic relationships. First, we generate multiscale candidate samples by applying several pooling windows with different sizes on a feature map, where different windows may represent different parts of the objects in the image. Then, we prune the sample set through threshold-based criteria to select appropriate samples for feature representation learning. Finally, Hi-CL is performed to learn the pixel-to-component consistency with the pruned samples. Our method is easy to be applied on existing semantic segmentation models and obtains consistent improvement. Furthermore, we achieve state-of-the-art results on three popular benchmarks, including Cityscapes, ADE20K, and COCO Stuff datasets.
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http://dx.doi.org/10.1109/TNNLS.2024.3491782 | DOI Listing |
Radiol Adv
September 2024
Department of Radiology, Northwestern University and Northwestern Medicine, Chicago, IL, 60611, United States.
Background: In clinical practice, digital subtraction angiography (DSA) often suffers from misregistration artifact resulting from voluntary, respiratory, and cardiac motion during acquisition. Most prior efforts to register the background DSA mask to subsequent postcontrast images rely on key point registration using iterative optimization, which has limited real-time application.
Purpose: Leveraging state-of-the-art, unsupervised deep learning, we aim to develop a fast, deformable registration model to substantially reduce DSA misregistration in craniocervical angiography without compromising spatial resolution or introducing new artifacts.
Front Oncol
August 2025
Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.
Purpose: Identifying radiomics features that help predict whether glioblastoma patients are prone to developing epilepsy may contribute to an improvement of preventive treatment and a better understanding of the underlying pathophysiology.
Materials And Methods: In this retrospective study, 3-T MRI data of 451 pretreatment glioblastoma patients (mean age: 61.2 ± 11.
Rev Cardiovasc Med
August 2025
Department of Cardiovascular Medicine, University Hospital Leuven, 3000 Leuven, Belgium.
Intravascular optical coherence tomography (OCT) has represented a revolutionary invasive imaging method, offering high-resolution cross-sectional views of human coronary arteries, thereby promoting a significant evolution in the understanding of vascular biology in both acute and chronic coronary pathologies. Since the development of OCT in the early 1990s, this technique has provided detailed insights into vascular biology, enabling a more thorough assessment of coronary artery disease (CAD) and the impact of percutaneous coronary intervention (PCI). Moreover, a series of recent clinical trials has consistently demonstrated the clinical benefits of intravascular imaging (IVI) and OCT-guided PCI, showing improved outcomes compared to angiography-guided procedures, particularly in cases of complex coronary pathology.
View Article and Find Full Text PDFCureus
August 2025
Physiology, SGT University, Gurugram, IND.
Introduction Simulation-based training has been a vital part of medical education since Competency-Based Medical Education (CBME) was introduced, and new guidelines since 2023 have expanded to include simulation as a mandatory methodology of teaching. This method enables learners to build and develop both technical and non-technical abilities in a safe and controlled setting, enhancing their preparedness for real-life medical scenarios. Simulation-based training improves skill acquisition and retention and enhances learners' confidence, reduces anxiety, reinforces learning, corrects errors, and promotes reflective practice, in contrast with the traditional method of teaching.
View Article and Find Full Text PDFAm J Psychiatry
September 2025
Department of Psychiatry, School of Medicine, Yale University, New Haven.
This review examines ketamine's neurotoxic potential across preclinical and clinical studies. The authors synthesized data from preclinical models, then integrated findings from human clinical trials of esketamine and observational studies in recreational users. Animal studies have found that repeated or high-dose subanesthetic ketamine administration results in consistent excitotoxic neuronal damage and lasting cognitive deficits, especially in perinatal animals.
View Article and Find Full Text PDF