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Innovations in electrophysiological recordings and computational analytic techniques enable high-resolution analysis of neural traveling waves. Here, we present a protocol for the detection and analysis of traveling waves from multi-day microelectrode array human electrophysiological recordings through a multi-linear regression statistical approach using point estimator data. We describe steps for traveling wave detection, feature characterization, and propagation pattern analysis. This protocol may improve our understanding of the coordination of neurons during non-oscillatory neural dynamics. For complete details on the use and execution of this protocol, please refer to Smith et al..
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http://dx.doi.org/10.1016/j.xpro.2025.103659 | DOI Listing |
Chaos
September 2025
Indian Institute of Science Education and Research, Tirupati, Andhra Pradesh 517507, India.
Adaptation in complex systems implies a natural ability to change. In networks, adaptation may include a change in structural connectivity, which can lead to a change in collective behavior. When dihedral symmetry is present, i.
View Article and Find Full Text PDFiScience
September 2025
Instituto de Neurociencias CSIC-UMH, Alicante, Spain.
Explaining the macroscopic activity of a neuronal population from its microscopic properties poses a great challenge, not just because of the many local agents that play a role, but due to the impact of long-range connections from other brain regions. We used a computational model to explore how local and global components of a network shape the slow wave activity (SWA). A sensitivity analysis allowed us to explore how local properties and long-range connections shaped the SWA of a population and its neighbors.
View Article and Find Full Text PDFbioRxiv
August 2025
Janelia Research Campus, HHMI, Ashburn VA, USA.
All cells in an animal collectively ensure, moment-to-moment, the survival of the whole organism in the face of environmental stressors. Physiology seeks to elucidate the intricate network of interactions that sustain life, which often span multiple organs, cell types, and timescales, but a major challenge lies in the inability to simultaneously record time-varying cellular activity throughout the entire body. We developed WHOLISTIC, a method to image second-timescale, time-varying intracellular dynamics across cell-types of the vertebrate body.
View Article and Find Full Text PDFAdv Sci (Weinh)
August 2025
Dipartimento di Psicologia, Università di Bologna and Centro studi e ricerche in Neuroscienze Cognitive, Università di Bologna, Cesena, Italy.
Perception relies on hierarchical processes integrating sensory data into higher-order models about the world. In the sensory domain, this hierarchy also involves horizontal pathways aiding interhemispheric interactions. For example, recent focus on the V5-V5 network revealed its role in motion processing.
View Article and Find Full Text PDFMicromachines (Basel)
July 2025
Research Center in Industrial Technologies CRTI, Cheraga, P.O. Box 64, Algiers 16014, Algeria.
The propagation of interface acoustic waves (IAWs) along rotated YX-LiNbO/SU-8/ZX-Si structures is theoretically investigated to identify the Y-rotation angles that support the efficient propagation of low-loss modes guided along the structure's interface. A three-dimensional finite element analysis was performed to simulate IAW propagation in the layered structure and to optimize design parameters, specifically the thicknesses of the platinum (Pt) interdigital transducers (IDTs) and the SU-8 adhesive layer. The simulations revealed the existence of two types of IAWs travelling at different velocities under specific Y-rotated cuts of the LiNbO half-space.
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