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Objective: Mechanical thrombectomy (MT) is an important procedure in the treatment of acute cerebral infarction, and its effectiveness depends largely on timely intervention after the onset. In the United States, a tiered accreditation system of stoke centers has been established to provide MT efficiently. In Japan, however, despite the large number of medical institutions performing MT, the establishment of a tiered accreditation system has yet to be seen. The low number of cases treated per institution raises concerns about the economic sustainability of MT in Japan because significant capital and human resource investment are required. This study aims to investigate the cost structure of MT procedure and the break-even point in 2 different hospital settings in Japan.
Methods: We conducted a detailed cost analysis of MT at 2 distinct hospitals: Hospital A, a large public hospital in a government-designated city, and Hospital B, a private non-profit hospital in the Tokyo metropolitan area. Data collection involved face-to-face interviews with department heads and a structured survey based on the Japanese Hospital Accounting Standards, focusing on material, labor, and facility-related costs. Break-even points were calculated considering both fixed and variable costs, with adjustments made for the shared use of facilities in Hospital B.
Results: The total cost per case was 349256 yen in Hospital A and 245150 yen in Hospital B, respectively. The total cost per case was elevated to 559866 yen assuming only MT was performed at Hospital B. This figure was significantly higher than the reimbursement price of MT (331500 yen). The number of procedures needed to exceed the break-even point for MT was approximately 290 cases per year in Hospital A and 125 cases per year in Hospital B, respectively.
Conclusion: We conducted a break-even analysis of MT based on an interview survey. The number of cases required to cross the break-even point for MT alone was much higher than the actual number of MT procedures being performed in the 2 hospitals.
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http://dx.doi.org/10.5797/jnet.oa.2024-0058 | DOI Listing |
Front Vet Sci
August 2025
Department of Animal and Public Health, Faculty of Veterinary Medicine, Eduardo Mondlane University (UEM), Maputo, Mozambique.
Background: Wheat bran (WB) and biscuit crumbs (BC) offer alternative feed sources for laying hens, potentially improving productivity and economic efficiency.
Objective: This work evaluated the partial replacement of maize meal with WB or BC, with or without the addition of CECT 5940, on the productive and economic performance of laying hens.
Methods: Five treatments were allocated as follows: T1: a basal diet; T2: a basal diet where 20% of maize meal was replaced by WB; T3: a basal diet that included 20% of WB plus CECT 5940; T4: a basal diet where 20% of maize meal was replaced by BC; and T5: a basal diet that included 20% of BC plus CECT 5940.
BMC Health Serv Res
July 2025
Department of Health Consumer Protection and Pharmacy Administration, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand.
Background: Robotic systems for chemotherapy preparation offer improved accuracy and staff safety but require substantial capital investment. This study assessed the economic performance of a domestically developed robotic chemotherapy compounding system at Udon Thani Cancer Hospital and its service expansion to a network hospital in Thailand.
Methods: A descriptive study with economic evaluation was conducted, including cost-benefit analysis, unit cost analysis, and break-even analysis from both provider and health system perspectives.
Intensive Care Med
August 2025
Department of Biomedical Sciences, Simulation Center, Humanitas University, Pieve Emanuele, Italy.
Purpose: Although healthcare crises are infrequent, they may place extraordinary stress on Intensive Care Units (ICUs), often exposing critical weaknesses in workforce planning and resulting in acute staffing shortages. This study presents a comprehensive economic evaluation of large-scale, rapid ICU workforce upskilling as a strategic response to such pressures. Specifically, we assess the cost-effectiveness, economic sustainability, and resilience-building potential of these interventions during crisis conditions.
View Article and Find Full Text PDFEur Radiol
July 2025
Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Objective: To evaluate the cost-effectiveness of AI-assisted digital mammography (AI-DM) compared to conventional biennial breast cancer digital mammography screening (cDM) with double reading of screening mammograms, and to investigate the change in cost-effectiveness based on four different sub-strategies of AI-DM.
Materials And Methods: A decision-analytic state-transition Markov model was used to analyse the decision of whether to use cDM or AI-DM in breast cancer screening. In this Markov model, one-year cycles were used, and the analysis was performed from a healthcare perspective with a lifetime horizon.
Lancet Reg Health West Pac
June 2025
Department of Health Economics Wellbeing and Society, The Australian National University, Canberra, ACT, Australia.
Background: Whole Genome Sequencing (WGS) is a powerful technology for monitoring and detecting outbreaks of infectious pathogens, including non-typhoidal (NTS). Despite its higher cost than traditional typing methods, WGS offers numerous advantages, including higher resolution and potentially quicker turnaround time. However, evidence regarding its effectiveness in NTS surveillance has predominantly stemmed from micro-simulations or small-scale data.
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