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Objectives: Several studies have demonstrated the potential of tin-prefiltration to reduce radiation dose while maintaining diagnostic image quality for musculoskeletal imaging. Still, no study has reported data on the impact of tin-prefiltration on radiation dose reduction for clinical routine scanning.
Materials And Methods: Retrospective inclusion of 300 clinically indicated CT scans of the pelvis, knee, and ankle before January 2020 (without tin filter) and after December 2020 (with tin filter). For each joint, 50 examinations with tin-prefiltration and 50 examinations without tin-prefiltration were selected. Dose parameters were extracted, calculated, and compared. Subjective and quantitative parameters for image quality were assessed.
Results: The CTDI, DLP, and effective dose were reduced significantly in all tin-prefiltered examinations compared to the non-tin-prefiltered examinations (p < 0.001): CTDI was 65% lower in the pelvis, 73% lower in the knee, and 54% lower in the ankle. This reduced the effective dose of 61%, 71%, and 60%, respectively. In absolute numbers, the reduction of the median effective dose delivered in a single CT scan of the pelvis was - 2.29 mSv, - 0.15 mSv for the knee, and - 0.03 mSv for the ankle. No difference in diagnostic image quality, depiction of bone anatomy and soft tissues, and image artifacts was observed (p > 0.05). Subjective and objective image noise was higher in tin-prefiltered pelvis CT (p < 0.001).
Conclusion: The implementation of tin-prefiltration in clinical routine scan protocols significantly reduced the effective radiation dose for unenhanced CT scans of the lower extremities between 60 and 70%.
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http://dx.doi.org/10.1007/s00256-025-04897-3 | DOI Listing |
Clin Transl Oncol
September 2025
Department of Radiation Oncology, Vithas La Milagrosa University Hospital, Madrid, 28010, Spain.
This narrative review analyzes current evidence comparing single-session and two-session approaches in Stereotactic Body Radiation Therapy (SBRT) and high-dose-rate (HDR) brachytherapy for localized prostate cancer. These ultra-hypofractionated strategies deliver high-precision ablative doses while minimizing exposure to normal tissues. SBRT regimens with fewer than five fractions show tumor control comparable to conventional treatments, offering reduced treatment burden and increased convenience.
View Article and Find Full Text PDFJ Robot Surg
September 2025
Department of Pediatric Surgery, Affiliated Hospital of North Sichuan Medical College (Wenhua Road Campus), No. 57, Section 2 of Wenhua Road, Shunqing District, Nanchong City, 637000, Sichuan Province, People's Republic of China.
This study aims to systematically assess the therapeutic effectiveness of TiRobot-assisted percutaneous kyphoplasty or vertebroplasty in managing osteoporotic thoracolumbar compression fractures. Previous studies have suggested that TiRobot-assisted techniques outperform conventional manual procedures in treating this condition, but relevant conclusions remain controversial. A thorough literature retrieval was carried out across 4 major databases: PubMed, Embase, the Cochrane Library, and Web of Science.
View Article and Find Full Text PDFRadiother Oncol
September 2025
Department of Radiation Oncology, University Hospital Bonn, Bonn, Germany; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany. Electronic address:
Background: In recent years, intraoperative radiotherapy (IORT) with low-energy X-rays is emerging as an alternative to postoperative stereotactic radiotherapy (SRT) of the resection cavity in patients with resectable brain metastases (BMs).
Methods: We performed a systematic review of the MEDLINE, Embase, and Scopus databases, including all original articles on IORT for resectable BMs from 2015 to 2025. Data on safety, local control, and survival outcomes were collected.
Radiother Oncol
September 2025
Amsterdam UMC, Location University of Amsterdam, Department of Neurosurgery, Meibergdreef 9, Amsterdam, the Netherlands; Amsterdam Neuroscience, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands.
Background And Purpose: Staged Gamma Knife radiosurgery (SGKRS) delivers high-dose radiotherapy to large brain metastases (BM) in two or three fractions with a time interval of several weeks. Various systemic treatments have also demonstrated favorable intracranial responses. Therefore, the outcome of patients undergoing radiosurgery and systemic treatment for large BM is of high interest but unknown.
View Article and Find Full Text PDFRadiother Oncol
September 2025
Canadian Cancer Trials Group, Queen's University, Kingston, ON, Canada.
Purpose/objectives: Low Dose-Rate Brachytherapy (LDR) and High Dose-Rate Brachytherapy (HDR) are options for favorable risk prostate cancer. We hypothesized that HDR provides comparable disease control with less urinary toxicity. Primary objective was to determine prostate cancer control at 48 months, defined as a PSA < 0.
View Article and Find Full Text PDF