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Introduction: The trend of older pregnant women and infertile women in South Korea, who are influencing the low birth rate, is on the rise. Older infertile women earnestly hoped for pregnancy and persisted in undergoing assisted reproductive technology multiple times. However, contrary to their wishes, they experienced failure to conceive.
Materials And Method: This study is qualitative research aimed at exploring the essential meaning of the experiences of women over 35 who have faced pregnancy failure after assisted reproductive technology.
Results: The average age of the participants in this study was 41.8 years, and they underwent an average of 5.7 assisted reproductive treatments after their infertility diagnosis. Through in-depth interviews with the participants, 120 meaningful statements were derived, which were classified into 23 themes, 9 theme clusters, and 4 categories. The four categories were "struggles and trials regarding assisted reproductive technology", "the challenging treatment journey", "the journey of overcoming sadness", and "the value and happiness gained from experience".
Conclusion: The results of this study showed that infertile women over 35, despite failing to conceive after assisted reproductive technology, were able to overcome their sadness and move towards personal growth. Therefore, various methods should be sought to support the psychological growth of women undergoing assisted reproductive technology.
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http://dx.doi.org/10.3389/frph.2025.1515086 | DOI Listing |
Eur Radiol Exp
September 2025
Center for MR-Research, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Background: Fetal MRI is increasingly used to investigate fetal lung pathologies, and super-resolution (SR) algorithms could be a powerful clinical tool for this assessment. Our goal was to investigate whether SR reconstructions result in an improved agreement in lung volume measurements determined by different raters, also known as inter-rater reliability.
Materials And Methods: In this single-center retrospective study, fetal lung volumes calculated from both SR reconstructions and the original images were analyzed.
J Assist Reprod Genet
September 2025
Bahçeci Fulya IVF Center, Infertility Clinic, Istanbul, Turkey.
Purpose: To assess the intra-individual variability of serum progesterone (P) levels on embryo transfer (ET) day, when the same dose of intramuscular progesterone (IM-P) was used in two consecutive hormone replacement therapy (HRT) frozen embryo transfer (FET) cycles.
Methods: A total of 75 patients undergoing two consecutive HRT-FET cycles in one year performed at Bahceci Ankara IVF Center between November 2019 and February 2022 were retrospectively analyzed. Serum P levels were measured at the 117th-119th hours of support by a single laboratory.
Mol Hum Reprod
September 2025
Department of Obstetrics and Gynecology, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Infertility impacts up to 17.5% of reproductive-aged couples worldwide. To aid in conception, many couples turn to assisted reproductive technology, such as IVF.
View Article and Find Full Text PDFArch Gynecol Obstet
September 2025
Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Objective: To investigate adverse pregnancy and delivery outcomes in women with GDMA1 during pregnancies conceived through fertility treatments.
Methods: This population-based retrospective cohort study examined adverse pregnancy and delivery outcomes in pregnancies affected by GDMA1 following fertility treatments compared to those conceived naturally. Women with GDMA1 who conceived via fertility treatments were classified as cases, while those who conceived naturally were designated as controls.
Paediatr Perinat Epidemiol
September 2025
Department of Epidemiology and Occupational Health, McGill University, Montréal, Quebec, Canada.
Background: Studies show that foetal and birthweight-for-gestational age centiles are poor predictors of serious neonatal morbidity and neonatal mortality (SNMM) in univariable models.
Objective: We assessed the predictive performance of multivariable SNMM models based on maternal/pregnancy characteristics, with and without birthweight centiles.
Methods: The study was based on all live births in the United States, 2019-2021, with data obtained from the period live birth-infant death files of the National Center for Health Statistics.