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Objective: This study aimed to explore a novel method that integrates the segmentation guidance classification and the diffusion model augmentation to realize the automatic classification for tibial plateau fractures (TPFs).
Methods: YOLOv8n-cls was used to construct a baseline model on the data of 3781 patients from the Orthopedic Trauma Center of Wuhan Union Hospital. Additionally, a segmentation-guided classification approach was proposed. To enhance the dataset, a diffusion model was further demonstrated for data augmentation.
Results: The novel method that integrated the segmentation-guided classification and diffusion model augmentation significantly improved the accuracy and robustness of fracture classification. The average accuracy of classification for TPFs rose from 0.844 to 0.896. The comprehensive performance of the dual-stream model was also significantly enhanced after many rounds of training, with both the macro-area under the curve (AUC) and the micro-AUC increasing from 0.94 to 0.97. By utilizing diffusion model augmentation and segmentation map integration, the model demonstrated superior efficacy in identifying Schatzker I, achieving an accuracy of 0.880. It yielded an accuracy of 0.898 for Schatzker II and III and 0.913 for Schatzker IV; for Schatzker V and VI, the accuracy was 0.887; and for intercondylar ridge fracture, the accuracy was 0.923.
Conclusion: The dual-stream attention-based classification network, which has been verified by many experiments, exhibited great potential in predicting the classification of TPFs. This method facilitates automatic TPF assessment and may assist surgeons in the rapid formulation of surgical plans.
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http://dx.doi.org/10.1007/s11596-025-00008-4 | DOI Listing |
RSC Adv
September 2025
Laboratory of Spectroscopic Characterization and Optical Materials, Faculty of Sciences, University of Sfax B.P. 1171 3000 Sfax Tunisia
Lithium metavanadate (LiVO) is a material of growing interest due to its monoclinic 2/ structure, which supports efficient lithium-ion diffusion through one-dimensional channels. This study presents a detailed structural, electrical, and dielectric characterization of LiVO synthesized a solid-state reaction, employing X-ray diffraction (XRD), scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDS), and impedance/dielectric spectroscopy across a temperature range of 473-673 K and frequency range of 10 Hz to 1 MHz. XRD and Rietveld refinement confirmed high crystallinity and single-phase purity with lattice parameters = 10.
View Article and Find Full Text PDFAdv Healthc Mater
September 2025
National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou, 215123, China.
Melasma is a facial hyperpigmentation disease that significantly impacts patients' quality of life. Clinical treatment is limited by the short half-lives and hydrophilicity of drugs, necessitating release curve optimization to maintain a stable therapeutic concentration for an extended period. This article utilizes natural biomaterials to design a core-shell structured microneedle, combining the "immediate release" and "delayed release" module to achieve programmed drug release.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
State Key Laboratory of Advanced Drug Delivery and Release Systems, Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.
Photo-responsive systems provide a powerful tool to reversibly regulate enzyme activity. However, inhibitor-based strategies, though widely used, are often restricted to specific enzymes. Noninhibitor strategies, such as enzyme surface modification or genetic mutation, often compromise structural integrity or residual activity.
View Article and Find Full Text PDFEnviron Monit Assess
September 2025
School of Geological Survey, China University of Geosciences, Wuhan, 430074, China.
Cadmium (Cd) contamination in water poses a critical global challenge. A novel nanocomposite, montmorillonite (Mt)-supported nanoscale zero-valent iron (Mt-nZVI), synthesized by liquid phase reduction, offers a promising method for effectively removing Cd. The material underwent characterization through various techniques, including X-ray diffraction (XRD) and Scanning Electron Microscope(SEM).
View Article and Find Full Text PDFExp Neurol
September 2025
CNRS UMR 5536 RMSB, University of Bordeaux, Bordeaux, France; Basic Science Department, Loma Linda University School of Medicine, Loma Linda, CA, USA; CNRS UMR 7372 CEBC, La Rochelle University, Villiers-en-Bois, France.
Introduction: The vulnerability of white matter (WM) in acute and chronic moderate-severe traumatic brain injury (TBI) has been established. In concussion syndromes, including preclinical rodent models, lacking are comprehensive longitudinal studies spanning the mouse lifespan. We previously reported early WM modifications using clinically relevant neuroimaging and histological measures in a model of juvenile concussion at one month post injury (mpi) who then exhibited cognitive deficits at 12mpi.
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