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Skin cancer is widespread and can be potentially fatal. According to the World Health Organisation (WHO), it has been identified as a leading cause of mortality. It is essential to detect skin cancer early so that effective treatment can be provided at an initial stage. In this study, the widely-used HAM10000 dataset, containing high-resolution images of various skin lesions, is employed to train and evaluate. Our methodology for the HAM10000 dataset involves balancing the imbalanced dataset by augmenting images followed by splitting the dataset into train, test and validation set, preprocessing the images, training the individual models Xception, InceptionResNetV2 and MobileNetV2, and then combining their outputs using fuzzy logic to generate a final prediction. We examined the performance of the ensemble using standard metrics like classification accuracy, confusion matrix, etc. and achieved an impressive accuracy of 95.14% and the result demonstrates the effectiveness of our approach in accurately identifying skin cancer lesions. To further assess the efficiency of the model, additional tests have been performed on the DermaMNIST dataset from the MedMNISTv2 collection. The model performs well on the dataset and transcends the benchmark accuracy of 76.8%, achieving 78.25%. Thus the model is efficient for skin cancer classification, showcasing its potential for clinical applications.
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http://dx.doi.org/10.1038/s41598-025-90423-3 | DOI Listing |
Int J Nurs Knowl
September 2025
Luciano Feijão College, Sobral, Ceará, Brazil.
Purpose: To clinically validate the nursing diagnosis "Inadequate Nutritional Intake" based on elements identified within a specific situation theory framework in the context of children with cancer.
Methods: This is a diagnostic accuracy study following the Standards for Reporting Diagnostic Accuracy Studies (STARD) protocol. Specifically, it refers to the clinical validation phase of the nursing diagnosis Inadequate nutritional intake, using a cross-sectional design.
JMIR Dermatol
September 2025
College of Osteopathic Medicine, Rocky Vista University, 8401 S Chambers Road, Parker, CO, 80112, United States, 1 9253236431.
Dermal fillers have gained increasing popularity for their ability to enhance facial symmetry, restore volume, and improve skin texture. However, their use in patients with cancer undergoing active chemotherapy and radiation therapy poses unique challenges, as these treatments can alter both the safety profile and efficacy of filler procedures. Chemotherapy can interfere with normal wound healing and immune responses, warranting a more cautious and individualized approach when considering dermal fillers in this population.
View Article and Find Full Text PDFAerosp Med Hum Perform
September 2025
Introduction: Pilots have an increased incidence of cutaneous melanoma compared to the general population; occupational exposure to ultraviolet (UV) radiation is one of several potential risk factors. Cockpit windshields effectively block UVB (280-315 nm) but further analysis is needed for UVA (315-400 nm). The objective of this observational study was to assess transmission of UVA through cockpit windshields and to measure doses of UVA at pilots' skin under daytime flying conditions.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
School of Life Sciences, Anhui Medical University, Hefei, 230032, China; Translational Research Institute of Henan Provincial People's Hospital, Henan International Joint Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial Key Laboratory of Long Non-coding RNA and Cancer Metaboli
Melanoma is the most aggressive and lethal form of skin cancer, posing significant challenges for prognosis assessment and treatment. Recently, metabolic reprogramming and epigenetic regulation have gained attention for their roles in cancer progression. The role of the key metabolic enzyme dihydrolipoic acid succinyltransferase (DLST) in cancer is currently unclear.
View Article and Find Full Text PDFBiomaterials
August 2025
Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA. Electronic address:
Wearable bioelectronics have transformed modern biomedical applications by enabling seamless integration with biological tissues, providing continuous, comprehensive, and personalized healthcare. Skin cancer, particularly melanoma, poses a significant clinical challenge due to its high metastatic potential and associated mortality. Traditional diagnostic approaches face limitations in accuracy, accessibility, and reproducibility, while existing treatments are often constrained by systemic toxicity and therapeutic resistance.
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